24244-60-8

Basic information

• Product Name: 2-PHENYLSULFONYLPRIDINE
• Synonyms: 2-PHENYLSULFONYLPRIDINE;2-PHENYLSULFONYLPRIDINE (ALT ROUTE);2-PHENYLSULFONYLPRIDINE (R&D INCLUDED);2-(phenylsulfonyl)pyridine;2-Benzene-sulfonyl-pyridine;BSP 2-Benzene-sulfonyl-pyridine
• CAS NO: 24244-60-8
• Molecular Formula: C₁₁H₉NO₂S
• Molecular Weight: 219.263
• Product Categories: Heterocycle-Pyridine series
• Mol File: 24244-60-8.mol
• Article Data: 24

Chemical Properties

• Melting Point: 93-95 °C
• Boiling Point: 407.3 °C at 760mmHg
• Flash Point: 200.1 °C
• Appearance: /
• Density: 1.282
• Vapor Pressure: 1.8E-06mmHg at 25°C
• Refractive Index: 1.594
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -1.84±0.19(Predicted)
• CAS DataBase Reference: 2-PHENYLSULFONYLPRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PHENYLSULFONYLPRIDINE(24244-60-8)
• EPA Substance Registry System: 2-PHENYLSULFONYLPRIDINE(24244-60-8)

Safety Data

• Hazardous Substances Data: 24244-60-8(Hazardous Substances Data)

Usage

Uses

2-(Phenylsulfonyl)pyridine is a useful building block in organic synthesis.

InChI:InChI=1/C11H9NO2S/c13-15(14,10-6-2-1-3-7-10)11-8-4-5-9-12-11/h1-9H

Upstream product

• 109-09-1 2-chloropyridine 
• 873-55-2 sodium benzenesulfonate 
• 694-59-7 pyridine N-oxide 
• 98-09-9 benzenesulfonyl chloride 
• 3111-54-4 2-phenylsulfanylpyridine 
• 109-04-6 2-bromo-pyridine 
• 5029-67-4 2-iodopyridine 
• 780-69-8 triethoxyphenylsilane 
• 4930-98-7 pyrid-2-ylhydrazine 
• 108-98-5 thiophenol 
• 98-80-6 phenylboronic acid 
• 420-04-2 CYANAMID 
• 89818-46-2 phenyl 2-pyridyl sulphoxide 
• 80-17-1 benzenesufonyl hydrazide 

Downstream Products

• 101-82-6 2-Benzylpyridine 
• 1035920-14-9 (2-chlorophenyl)[2-(phenylsulfonyl)pyridin-3-yl]methanol 
• 1423122-99-9 1-benzyl-2-((2-iodo-4-cyano-phenyl)methyl)pyridinium bromide 

Relevant articles and documents

Synthesis and antifungal activities of pyridine bioisosteres of a bismuth heterocycle derived from diphenyl sulfone

– Heterocyclic iodobismuthanes 7–9 [IBi(C6H4-2-SO2C5H3N-1′-)] derived from phenyl pyridinyl sulfones were synthesized. Their antifungal activities against the yeast Saccharomyces cerevisiae were compared with those of halobismuthanes [XBi(RC6H3-2-SO2C6H4-1′-)] (1: X=Cl; 2: X=I, R=H) derived from diphenyl sulfone derivatives to determine how the bioisosteric replacement of the benzene ring in 2 with the pyridine ring in 7–9 affects their activities. The antifungal activities of 7–9 were higher or comparable to those of 1 and 2. The DFT calculations suggested that the generation of the antifungal activity of the bismuthanes was well understood by the nucleophilic addition of methanethiolate anion as a model biomolecule at the bismuth atom to give an intermediate ate complex.

Method for synthesizing sulfone compounds under photocatalysis condition

The invention belongs to the technical field of compound preparation, and particularly relates to a method for synthesizing sulfone compounds under a photocatalysis condition. Aromatic hydrazine and sulfinate are used as raw materials, and under the action of alkali and a solvent, a sulfone compound is generated through reaction under the condition of air or oxygen under the illumination of visible light. According to the method disclosed by the invention, aryl hydrazine is used as an arylation reagent, polyacid salt is used as a catalyst or an organic photosensitizer is used as a catalyst, and the sulfones compound can be efficiently synthesized by coupling with sulfinate under the condition of room temperature through visible light irradiation. The method has good substrate universalityand relatively mild reaction conditions, is not only a substitute for synthesizing sulfone compounds by coupling from simple substrates reported at present, but also broadens the new application of the polyacid salt in the field of photocatalysis.

Sulfoxide and Sulfone Synthesis via Electrochemical Oxidation of Sulfides

The oxidation of diaryl sulfides and aryl alkyl sulfides to the corresponding sulfoxides and sulfones under electrochemical conditions is reported. Sulfoxides are selectively obtained in good yield under a constant current of 5 mA for 10 h in DMF, while sulfones are formed as the major product under a constant current of 10 or 20 mA for 10 h in MeOH. The oxygen of both the sulfoxide and sulfone function is derived from water.