2426-07-5

Basic information

• Product Name: 1,2,7,8-DIEPOXYOCTANE
• Synonyms: 1,4-Buthylenebis(oxirane);1,4-Butylenebis(oxirane);2,2'-(Butane-1,4-diyl)bisoxirane;2,2'-Tetramethylenebisoxirane;1,2,7,8-Diepoxyoctane,97%;1,2,7,8-Diepoxyoctane (CAS:2426-07-5);1,4-Di(oxiran-2-yl)butane;1,4-di(oxiran-2-yl)butane, 1,2,7,8-diepoxyoctane
• CAS NO: 2426-07-5
• Molecular Formula: C8H14O2
• Molecular Weight: 142.2
• EINECS: 219-375-9
• Product Categories: Oxiranes;Simple 3-Membered Ring Compounds;Epoxide Monomers;Monomers;Polymer Science
• Mol File: 2426-07-5.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 240 °C(lit.)
• Flash Point: 208 °F
• Appearance: /
• Density: 0.997 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0602mmHg at 25°C
• Refractive Index: n20/D 1.445(lit.)
• Storage Temp.: Store below +30°C.
• Solubility: 7g/l
• Water Solubility: Soluble in water (partly miscible), acetone and heptane.
• BRN: 104873
• CAS DataBase Reference: 1,2,7,8-DIEPOXYOCTANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,7,8-DIEPOXYOCTANE(2426-07-5)
• EPA Substance Registry System: 1,2,7,8-DIEPOXYOCTANE(2426-07-5)

Safety Data

• Hazard Codes: T
• Statements: 22-24-68-45
• Safety Statements: 36/37/39-45-53
• RIDADR: UN 2810 6.1/PG 3
• WGK Germany: 3
• RTECS: RG9450000
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 2426-07-5(Hazardous Substances Data)

Usage

Description

1,2,7,8-Diepoxyoctane is an organic compound characterized by the presence of two epoxy groups in its octane structure. It is a clear colorless to slightly yellow liquid and is widely utilized as an intermediate in organic chemical synthesis.

Uses

1. Used in Organic Chemical Synthesis:
1,2,7,8-Diepoxyoctane is used as an organic chemical synthesis intermediate for various applications, including the production of pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure with two epoxy groups allows for versatile reactions and functional group transformations, making it a valuable compound in the synthesis of complex organic molecules.
2. Used in the Suzuki Reaction:
In the field of organic chemistry, 1,2,7,8-Diepoxyoctane is also employed in the Suzuki reaction, a widely used method for the formation of carbon-carbon bonds, specifically in the synthesis of biaryl compounds. The Suzuki reaction is a cross-coupling reaction between an organoboron compound and an organohalide in the presence of a palladium catalyst, and 1,2,7,8-Diepoxyoctane can serve as a precursor or reactant in this process, contributing to the formation of diverse organic molecules with potential applications in various industries.

InChI:InChI=1/C8H14O2/c1(3-7-5-9-7)2-4-8-6-10-8/h7-8H,1-6H2/t7-,8-/m0/s1

Upstream product

• 871-84-1 1,7-Octadiyne 
• 52485-73-1 1,2-epoxy-7-octene 
• 3710-30-3 1,7-Octadiene 
• 37554-04-4 3,3'-dichloro-1,1'-oxy-bis-propan-2-ol 

Downstream Products

• 629-41-4 1,8-Octanediol 
• 19686-96-5 octane-2,7-diol 
• 1422211-00-4 benzyl ((S)-2-hydroxy-6-((R)-oxiran-2-yl)hexyl)carbamate 
• 1422211-01-5 benzyl ((S)-2-hydroxy-6-((S)-oxiran-2-yl)hexyl)carbamate 
• 1422211-20-8 tert-butyl ((S)-2-(benzyloxy)-6-((R)-oxiran-2-yl)hexyl)carbamate 
• 1422211-09-3 (S)-2-hydroxy-6-((R)-oxiran-2-yl)hexyl-4-methylbenzenesulfonate 
• 1309222-12-5 C₂₂H₂₆O₄S₂ 
• 1186107-43-6 5,5'-(2,7-dihydroxyoctane-1,8-diyl)bis(acetylazanediyl)bis(N₁,N₃-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-N₁,N₃-dimethylisophthalamide) 
• 638-54-0 1,8-octanedial 
• 1626-09-1 2,7-octanedione 
• 87378-11-8 1,8-Bis-(1-methyl-1-phenyl-ethylperoxy)-octane-2,7-diol 

Relevant articles and documents

Production of enantiopure chiral epoxides with e. Coli expressing styrene monooxygenase

Styrene monooxygenases are a group of highly selective enzymes able to catalyse the epoxidation of alkenes to corresponding chiral epoxides in excellent enantiopurity. Chiral compounds containing oxirane ring or products of their hydrolysis represent key building blocks and precursors in organic synthesis in the pharmaceutical industry, and many of them are produced on an industrial scale. Two-component recombinant styrene monooxygenase (SMO) from Marinobacterium litorale was expressed as a fused protein (StyAL2StyB) in Escherichia coli BL21(DE3). By high cell density fermentation, 35 gDCW/L of biomass with overexpressed SMO was produced. SMO exhibited excellent stability, broad substrate specificity, and enantioselectivity, as it remained active for months and converted a group of alkenes to corresponding chiral epoxides in high enantiomeric excess (>95–99% ee). Optically pure (S)-4-chlorostyrene oxide, (S)-allylbenzene oxide, (2R,5R)-1,2:5,6-diepoxyhexane, 2-(3-bromopropyl)oxirane, and (S)-4-(oxiran-2-yl)butan-1-ol were prepared by whole-cell SMO.

NOVEL BETA-HYDROXYLATED TERTIARY DIAMINES, A PROCESS FOR THEIR SYNTHESIS AND THEIR USE FOR ELIMINATING ACID COMPOUNDS A GASEOUS EFFLUENT

The invention relates to novel nitrogen compounds belonging to the family of tertiary diamines of general formula (I) below, wherein R is an alkanediyl radical —(CH2)n- with n=2, 3, 4, 5 or 6. The compound according to the invention is for example N,N,N′,N′-(tetramethyl)-1,6-diamino-2,5-hexanediol or N,N,N′,N′-(tetramethyl)-1,8-diamino-2,7-octanediol. The invention also relates to the method for preparing them and to their use for removing acid compounds contained in a gaseous effluent.

Absolute configuration for 1, n-glycols: A nonempirical approach to long-range stereochemical determination

The absolute configurations of 1,n-glycols (n = 2-12, 16) bearing two chiral centers were rapidly determined via exciton-coupled circular dichroism (ECCD) using a tris(pentafluorophenyl)porphyrin (TPFP porphyrin) tweezer system in a nonempirical fashion devoid of chemical derivatization. A unique "side-on" approach of the porphyrin tweezer relative to the diol guest molecule is suggested as the mode of complexation.