2426-84-8Relevant articles and documents
Mussel-inspired healing of a strong and stiff polymer
Chen, Ning,Qin, Liming,Pan, Qinmin
, p. 6667 - 6674 (2018)
Self-healability will greatly improve the reliability, service life and maintenance of synthetic materials. However, it remains a big challenge to realize the self-healing of a strong and stiff polymer due to its poor molecular mobility. Inspired by the h
Synthesis and in-vitro anti-hepatitis-B virus activity of 6H-[1]benzothiopyrano[4,3-b] quinolin-10-ols
Jia, Wei,Zhao, Yanfang,Li, Rongdong,Wu, Yanjiao,Li, Zebiao,Gong, Ping
, p. 507 - 512 (2009)
A series of 9-methoxy-6H-[1]benzothiopyrano[4,3-b]quinolin-10-ols with a Mannich side chain were synthesized and evaluated for their anti-Hepatitis B virus (HBV) activity in HepG2.2.15 cells. Some compounds showed significant anti-HBV activity with IC50 values less than 41 μM. Among them, compound 9b was the most effective anti-HBV agent (IC50 = 1.7 μM, SI = 60.3).
G-A CROSSLINKING CYTOTOXIC AGENTS
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, (2020/08/22)
The invention relates to a compound of formula (I): or salts, solvates, isomers or tautomers thereof, wherein; A is a group selected from: R1 is selected from H and halogen; either R2 is selected from -CH2-halogen, C1
POLYCYCLIC AMIDES AS CYTOTOXIC AGENTS
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, (2020/03/29)
The invention relates to a compound of formula (I): or pharmaceutically acceptable salts, solvates, tautomers, stereoisomers or mixtures thereof; wherein the fused ring moiety is a non-alkylating moiety; and wherein the compounds are useful as medicaments, in particular for use as a drug in an antibody-drug conjugate and in the treatment of a proliferative disease, a bacterial infection, a malarial infection and inflammation.