24295-27-0

Basic information

• Product Name: METHYL 3,5-DICHLORO-4-METHOXYBENZOATE
• Synonyms: METHYL 3,5-DICHLORO-4-METHOXYBENZENECARBOXYLATE;METHYL 3,5-DICHLORO-4-METHOXYBENZOATE;METHYL 3,5-DICHLORO-4-METHOXYBENZOATEA;3,5-Dichloro-4-methoxybenzoic acid methyl ester
• CAS NO: 24295-27-0
• Molecular Formula: C₉H₈Cl₂O₃
• Molecular Weight: 235.06
• Product Categories: Aromatic Esters
• Mol File: 24295-27-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 74-77
• Boiling Point: 325.5°Cat760mmHg
• Flash Point: 139.5°C
• Appearance: /
• Density: 1.341g/cm³
• Vapor Pressure: 0.00023mmHg at 25°C
• Refractive Index: 1.534
• CAS DataBase Reference: METHYL 3,5-DICHLORO-4-METHOXYBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3,5-DICHLORO-4-METHOXYBENZOATE(24295-27-0)
• EPA Substance Registry System: METHYL 3,5-DICHLORO-4-METHOXYBENZOATE(24295-27-0)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 24295-27-0(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 79, p. 1468, 1957 DOI: 10.1021/ja01563a053

InChI:InChI=1/C9H8Cl2O3/c1-13-8-6(10)3-5(4-7(8)11)9(12)14-2/h3-4H,1-2H3

Upstream product

• 3336-41-2 3,5-dichloro-4-hydroxybenzoic acid 
• 77-78-1 dimethyl sulfate 
• 74-88-4 methyl iodide 
• 17302-82-8 ethyl 3,5-dichloro-4-hydroxybenzoate 
• 124-41-4 sodium methylate 

Downstream Products

• 4892-23-3 3,5-dichloro-4-methoxybenzyl alcohol 
• 37908-97-7 3,5-dichloro-4-methoxybenzoic acid 
• 109047-54-3 (3,5-dichloro-4-methoxy-phenyl)-acetic acid 
• 98588-81-9 (3,5-dichloro-4-methoxy-phenyl)-acetonitrile 
• 98544-66-2 4-bromomethyl-2,6-dichloro-anisole 
• 27164-02-9 (3,5-dichloro-4-methoxy-phenyl)-acetic acid amide 
• 1027152-07-3 1-[4-(methylsulfonyl)phenyl]-2-(4-methoxy-3,5-dichlorophenyl)-4-trifluoromethyl-4-hydroxy-4,5-dihydro-1H-imidazole 
• 3336-38-7 3,5-dichloro-4-methyloxybenzonitrile 
• 249757-10-6 [(R)-(3,5-dichloro-4-methoxyphenyl)-(S)-(2-hydroxy-1-phenylethylamino)]acetonitrile 
• 193073-55-1 [(S)-(3,5-dichloro-4-methoxyphenyl)-(S)-(2-hydroxy-1-phenylethylamino)]acetic acid methyl ester 
• 441284-62-4 (Z)-2,6-dichloro-4-(1'-propenyl)anisole 
• 41727-58-6 3,5-dichloro-4-methoxybenzaldehyde 

Relevant articles and documents

Stereocontrolled total synthesis of (-)-kaitocephalin

(Chemical Equation Presented) This paper describes the successful implementation of a stereocontrolled strategy for the total chemical synthesis of the pyrrolidine-based alkaloid (-)-kaitocephalin. This scalable synthetic route profits from the strategic

Synthesis of (1R,2S)-1-(3′-chloro-4′-methoxyphenyl)-1,2- propanediol (trametol) and (1R,2S)-1-(3′,5′-dichloro-4′- methoxyphenyl)-1,2-propanediol, chlorinated fungal metabolites in the natural environment

(1R,2S)-1-(3′-Chloro-4′-methoxyphenyl)-1,2-propanediol (Trametol, 3), a metabolite of the fungus Trametes sp. IVP-F640 and Bjerkandera sp. BOS55, was synthesized by employing Sharpless asymmetric dihydroxylation as the key step. Similarly, the (1R,2S)-isomer of 1-(3′,5′-dichloro- 4′-methoxyphenyl)-1,2-propanediol (4), another metabolite of Bjerkandera sp. BOS55, was synthesized by asymmetric dihydroxylation.