2432-03-3Relevant articles and documents
Heterobifunctional Rotaxanes for Asymmetric Catalysis
Daniliuc, Constantin G.,Grimme, Stefan,Huber, Alexander,Jansen, Dennis,Niemeyer, Jochen,Pairault, No?l,Zhu, Hui
, p. 5102 - 5107 (2020)
Heterobifunctional rotaxanes serve as efficient catalysts for the addition of malonates to Michael acceptors. We report a series of four different heterobifunctional rotaxanes, featuring an amine-based thread and a chiral 1,1′-binaphthyl-phosphoric-acid-b
GABAA Receptor allosteric enhancement compounds and their preparation and use
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Paragraph 0054-0060, (2020/03/17)
A GABA A receptor allosteric enhancer compound and preparation and a use thereof are disclosed. The compound has a structure represented by formula (1). R 1 and R 2 are each independently selected from isopropyl and n-propyl; and when R 1 is n-propyl, R 2 is not isopropyl.
Activation and modulation of recombinant glycine and GABAAreceptors by 4-halogenated analogues of propofol
Germann, Allison L,Shin, Daniel J,Manion, Brad D,Edge, Christopher J,Smith, Edward H,Franks, Nicholas P,Evers, Alex S,Akk, Gustav
, p. 3110 - 3120 (2016/11/24)
Background and Purpose: Glycine receptors are important players in pain perception and movement disorders and therefore important therapeutic targets. Glycine receptors can be modulated by the intravenous anaesthetic propofol (2,6-diisopropylphenol). Howe