2433-95-6Relevant articles and documents
Ceramide and cerebroside from the stem bark of Ficus mucuso (Moraceae)
Bankeu, Jean Jules Kezetas,Mustafa, Sufyan Awad Alkarim,Gojayev, Anar Sahib,Lenta, Bruno Djakou,Tchamo Noungoue, Diderot,Ngouela, Silvere Augustin,Asaad, Khalid,Choudhary, Mohammed Iqbal,Prigge, Sean,Guliyev, Akif Alekper,Nkengfack, Augustin Ephrem,Tsamo, Etienne,Shaiq Ali, Muhammad
, p. 1661 - 1665 (2010)
Two new sphingolipids mucusamide (1) and mucusoside (2) have been isolated from methanol soluble part of the stem bark of Ficus mucuso WELW., together with fifteen known secondary metabolites including cellobiosylsterol (3), β-sitosterol (4), stigmasterol (5), β-sitosterol 3-O-β-D- glucopyranoside (6), lupeol acetate (7), ursolic acid (8), procatechuic acid (9), 2-methyl-5,7-dihydroxychromone 8-C-β-D-glucoside (10), apigenin (11), (-)-epicatechin (12), (+)-catechin (13), N-benzoyl-L-phenylalanilol (14), α-acetylamino-phenylpropyl α-benzoylaminophenylpropionate (15), asperphenamate (16) and bejaminamide (17). Structures of compounds 1 and 2 were elucidated by spectroscopic analysis and chemical methods.
Preliminary biological assay on cerebroside mixture from Euphorbia nicaeensis All. Isolation and structure determination of five glucocerebrosides
Cateni,Zilic,Falsone,Hollan,Frausin,Scarcia
, p. 809 - 817 (2007/10/03)
Preliminary studies of in vitro cytostatic activity on less polar fraction of the MeOH extract of the plant Euphorbia nicaeensis All., carried out on KB cells, have evinced a relatively low ability of extract to inhibit cell growth. Successive, five glucocerebrosides were isolated from the cerebroside molecular species obtained from this extract using normal and reversed phase column 'flash-chromatography'. The structures of these cerebrosides were determined on the basis of chemical and spectroscopic evidences. Mass spectrometry of dimethyl disulfide derivatives was useful for the determination of the double-bond positions in the long-chain bases.
Agelasphins, novel antitumor and immunostimulatory cerebrosides from the marine sponge Agelas mauritianus
Natori, Takenori,Morita, Masahiro,Akimoto, Kohji,Koezuka, Yasuhiko
, p. 2771 - 2784 (2007/10/02)
New glycosphingolipids, named agelasphins (1-8), have been isolated by antitumor and immunostimulatory bioassay-guided purification from an extract of a marine sponge, Agelas mauritianus. Strongly active agents in agelasphins had characteristic α-galactosylceramide structures, the isolation of which from natural products has not previously been reported. The absolute configurations of agelasphins were elucidated by the total synthesis.