2435-64-5

Basic information

• Product Name: Benzenesulfonamide,4-[2-[4-(dimethylamino)phenyl]diazenyl]-
• Synonyms: Benzenesulfonamide,4-[[4-(dimethylamino)phenyl]azo]- (9CI); Benzenesulfonamide, p-[[p-(dimethylamino)phenyl]azo]-(6CI,7CI,8CI); 4-Sulfonamido-4'-dimethylaminoazobenzene; Methyl Orange Amide
• CAS NO: 2435-64-5
• Molecular Formula: C₁₄H₁₆N₄O₂S
• Molecular Weight: 304.3674
• Mol File: 2435-64-5.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 527.5°Cat760mmHg
• Flash Point: 272.8°C
• Appearance: /
• Density: 1.28g/cm³
• Vapor Pressure: 3.23E-11mmHg at 25°C
• Refractive Index: 1.622
• CAS DataBase Reference: Benzenesulfonamide,4-[2-[4-(dimethylamino)phenyl]diazenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide,4-[2-[4-(dimethylamino)phenyl]diazenyl]-(2435-64-5)
• EPA Substance Registry System: Benzenesulfonamide,4-[2-[4-(dimethylamino)phenyl]diazenyl]-(2435-64-5)

Safety Data

• Hazardous Substances Data: 2435-64-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H16N4O2S/c1-18(2)13-7-3-11(4-8-13)16-17-12-5-9-14(10-6-12)21(15,19)20/h3-10H,1-2H3,(H2,15,19,20)/b17-16+

Upstream product

• 121-69-7 N,N-dimethyl-aniline 
• 63-74-1 sulfanilamide 
• 56512-49-3 dabsyl chloride 
• 14289-29-3 4-Sulfamoyl-benzenediazonium 

Downstream Products

• 1264265-16-8 N,N-bis(2-butynyl)-4-dimethylaminoazobenzene-4'-sulfonamide 

Relevant articles and documents

A chemosensor bearing sulfonyl azide moieties for selective chromo-fluorogenic hydrogen sulfide recognition in aqueous media and in living cells

A simple chemodosimeter based on a sulfonyl azide dye (1-Az), which displayed a highly selective response toward hydrogen sulfide anion in mixed aqueous media, was synthesised and characterised. Addition of hydrogen sulfide to acetonitrile/HEPES 1:1 solutions of 1-Az induced a clear colour change from red-orange to yellow, which was easily detected by the naked eye, and by an enhancement in the emission intensity. Other common anions, thiol-containing biomolecules and oxidants did not induce any noticeable colour or fluorescence modulation in the probe. The chemodosimeter also showed a good sensitivity, with limits of detection of 11.91 and 0.63 μM by using UV/Vis or fluorescence measurements, respectively. Moreover, 1-Az could be used for real-time fluorescence imaging of intracellular HS- at micromolar concentrations. Sensitive and selective chromogenic detection of hydrogen sulfide in aqueous environments was achieved with a simple sulfonyl azide derivative. Copyright

Carbonic anhydrase inhibitors. Inhibition of the Rv1284 and Rv3273 β-carbonic anhydrases from Mycobacterium tuberculosis with diazenylbenzenesulfonamides

A series of diazenylbenzenesulfonamides obtained from sulfanilamide or metanilamide by diazotization followed by coupling with phenols or amines, was tested for the inhibition of the β-carbonic anhydrases (CAs, EC 4.2.1.1) encoded by the genes Rv1284 and

Synthesis of non-proteinogenic phenylalanine derivatives by rhodium-catalyzed [2+2+2] cycloaddition reactions

Non-proteinogenic phenylalanine derivatives were efficiently prepared by Rh(I)-catalyzed [2+2+2] cycloaddition reactions between enantiopure and racemic propargylglycine amino acids, with different protective groups, and diynes. Diverse substituents, incl