24396-24-5

Basic information

• Product Name: Phenol, 2-(dimethoxymethyl)-
• Synonyms: Salicylaldehyd-dimethylacetal;dimethoxymethyl phenol;saliylaldehyde dimethyl acetal;2-dimethoxymethylphenol;salicylaldehyde dimethyl acetal;Phenol,2-(dimethoxymethyl)
• CAS NO: 24396-24-5
• Molecular Formula: C9H12O3
• Molecular Weight: 168.192
• Mol File: 24396-24-5.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: Phenol, 2-(dimethoxymethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 2-(dimethoxymethyl)-(24396-24-5)
• EPA Substance Registry System: Phenol, 2-(dimethoxymethyl)-(24396-24-5)

Safety Data

• Hazardous Substances Data: 24396-24-5(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 90-02-8 salicylaldehyde 
• 149-73-5 trimethyl orthoformate 
• 5663-67-2 2-acetoxybenzaldehyde 
• 431-47-0 trifluoroacetic acid-methyl ester 
• 124-41-4 sodium methylate 
• 89-95-2 2-methyl-benzyl alcohol 

Downstream Products

• 6842-36-0 2-(2-hydroxyphenyl)-1,3-dithiane 
• 119-36-8 methyl salicylate 
• 854280-48-1 (E)-1-(3-phenylallyloxy)-2-(dimethoxymethyl)benzene 
• 135053-29-1 2-(2-hydroxyethoxy) benzaldehyde acrylic acid ester 
• 134959-93-6 2-(2-dimethoxymethylphenoxy) ethyl acrylate 
• 1037288-04-2 C₁₇H₁₈O₄ 
• 90-02-8 salicylaldehyde 
• 1351353-32-6 dimethyl 2-(2-hydroxyphenyl)-1,3-dioxolane-4,5-dicarboxylate 
• 486998-80-5 dimethyl (4R-5R)-2-(2-hydroxyphenyl)-1,3-dioxolane-4,5-dicarboxylate 
• 1351353-30-4 diisopropyl 2-(2-hydroxyphenyl)-1,3-dioxolane-4,5-dicarboxylate 
• 1351353-22-4 2-{4-[benzyloxymethyl]-1,3-dioxolane-2-yl}phenol 
• 1351353-21-3 2-{(4R)-4-[benzyloxymethyl]-1,3-dioxolane-2-yl}phenol 
• 1351353-23-5 2-[(4S,5S)-4,5-bis(benzyloxymethyl)-1,3-dioxolane-2-yl]phenol 
• 1351353-26-8 diisopropyl (4R-5R)-2-(2-hydroxyphenyl)-1,3-dioxolane-4,5-dicarboxylate 

Relevant articles and documents

Chemical Synthesis and Biological Evaluations of Adiponectin Collagenous Domain Glycoforms

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Stereodivergent access to all four stereoisomers of chiral tetrahydrobenzo[f] [1,4]oxazepines, through highly diastereoselective multicomponent Ugi-Joullié reaction

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Preparation of acetals from aldehydes and alcohols under basic conditions

A new, simple protocol for the synthesis of acetals under basic conditions from non-enolizable aldehydes and alcohols has been reported. Such reactivity is facilitated by a sodium alkoxide along with a corresponding trifluoroacetate ester, utilizing formation of sodium trifluoroacetate as a driving force for acetal formation. The usefulness of this protocol is demonstrated by its orthogonality with various acid-sensitive protecting groups and by good compatibility with functional groups, delivering synthetically useful acetals complementarily to the synthesis under acidic conditions from aldehydes and alcohols.