24410-21-7Relevant articles and documents
Bronchodilating pyrido?2,3-d!pyrimidine derivatives
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, (2008/06/13)
A rapid-acting remedy for asthma having a bronchodilating action contains at least one pyrido?2,3-d!pyrimidine derivative represented by the general formula (A) or pharmaceutically acceptable salts or metal complexes thereof as an effective component: STR1 wherein R1 and R2 are the same or different and each of R1 and R2 is hydrogen, alkyl or benzyl; R3 is hydrogen, hydroxyl, dialkylaminomethyleneamino or --NH--X; X is hydrogen, alkyl, alkenyl, hydroxyl, amino, hydroxyalkyl, benzyl or acyl; R4 is hydrogen, alkyl, halogen, nitro, amino, hydroxyl, benzyloxy, cyano, carboxyl, alkoxycarbonyl, alkoxysulfonyl, aminosulfonyl, dialkylaminosulfonyl or sulfo; and R5 is hydrogen, alkyl or amino. The rapid-acting remedy for bronchial asthma is capable of relieving the symptom of laboring breath at the onset of asthma due to its excellent bronchodilating action. It can be used as a therapy not only for allergic asthma but also for various bronchial asthmas such as endogenous asthma, exogenous asthma and dust asthma.
DIETHYLAMINE AND TRIETHYLAMINE AS SOURCES OF THE DIENOPHILE COMPONENT IN THE REVERSE AZADIENE SYNTHESIS WITH DIMETHYLPYRIMIDO- AND --1,2,4-TRIAZINEDIONES AND 1,2,4,5-TETRAZINES
Shorshnev, S. V.,Esipov, S. E.,Kuz'menko, V. V.,Gulevskaya, A. V.,Pozharskii, A. F.,et al.
, p. 1289 - 1301 (2007/10/02)
Diethylamine (DEA) and triethylamine (TEA) can function as sources for the two-carbon component in the reverse azadiene synthesis.Reaction of 5,7-dimethylpyrimido-1,2,4-triazene-6,8-dione, 6,8-dimethylpyrimido--1,2,4-triazine-5,7-dione, or 1
U8NUSUAL REACTIONS OF DIMETHYLPYRIMIDO- AND -1,2,4-TRIAZINEDIONES WITH DIETHYLAMIN
Shorshnev, S.V.,Esipov, S.E.
, p. 231 (2007/10/02)
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