24410-58-0 Usage
General Description
4-Fluorobenzofuran is a chemical compound with the molecular formula C8H5FO. It is a derivative of benzofuran with a fluorine atom substituted at the 4-position of the benzene ring. 4-Fluorobenzofuran is considered to be a potential designer drug and has been identified as a psychoactive substance. It may act as a serotonin releasing agent and could potentially have stimulant and entactogenic effects. 4-Fluorobenzofuran is not approved for any medical or therapeutic use and is currently classified as a research chemical. Its potential effects and safety profile have not been thoroughly studied, and its recreational use is associated with health risks and legal consequences.
Check Digit Verification of cas no
The CAS Registry Mumber 24410-58-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,4,1 and 0 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 24410-58:
(7*2)+(6*4)+(5*4)+(4*1)+(3*0)+(2*5)+(1*8)=80
80 % 10 = 0
So 24410-58-0 is a valid CAS Registry Number.
24410-58-0Relevant articles and documents
Synthesis and structure-activity relationship of dihydrobenzofuran derivatives as novel human GPR119 agonists
Ye, Xiang-Yang,Morales, Christian L.,Wang, Ying,Rossi, Karen A.,Malmstrom, Sarah E.,Abousleiman, Mojgan,Sereda, Larisa,Apedo, Atsu,Robl, Jeffrey A.,Miller, Keith J.,Krupinski, John,Wacker, Dean A.
, p. 2539 - 2545 (2014/05/20)
Through appropriate medicinal chemistry design tactics and computer-assisted conformational modeling, the initial lead A was evolved into a series of dihydrobenzofuran derivatives 3 as potent GPR119 agonists. This Letter describes the optimization of general structure 3, including the substituent(s) on dihydrobenzofuran, the R1 attachment on right-hand piperidine nitrogen, and the left-hand piperidine/piperazine and its attachment R2. The efforts led to the identification of compounds 13c and 24 as potent human GPR119 modulators with favorable metabolic stability, ion channel activity, and PXR profiles.
