244158-06-3Relevant articles and documents
Double anionic cycloaromatization of 2-(6-substituted-3-hexene-1,5-diynyl)-benzonitriles initiated by methoxide addition
Wu, Ming-Jung,Lin, Chi-Fong,Chen, Shang-Hung
, p. 767 - 768 (1999)
Formula presented Treatment of 2-((3Z)-undecene-1,5-diynyl)benzonitrile with 5 equiv of sodium methoxide in refluxing methanol for 16 h gave 1-pentyl-6-methoxyphenanthridine in 12% yield, 1-pentyl-6-phenanthridone in 6% yield, and 2-(2-pentyl-6-methoxyphe
A Series of enediynes as novel inhibitors of topoisomerase I
Lin, Chi-Fong,Hsieh, Pei-Chen,Lu, Wen-Der,Chiu, Huey-Fen,Wu, Ming-Jung
, p. 1707 - 1711 (2007/10/03)
A series of acyclic enediynes, 2-((6-substituted)-3-hexen-1,5-diynyl)benzonitriles (8-11), display potent inhibition against topoisomerase I without the formation of active biradical intermediates and show inhibitory activity against topoisomerase I at 10