244621-31-6Relevant articles and documents
Design, synthesis, and biological activity of potent and selective inhibitors of blood coagulation factor Xa
Willardsen, J. Adam,Dudley, Danette A.,Cody, Wayne L.,Chi, Liguo,McClanahan, Thomas B.,Mertz, Thomas E.,Potoczak, Ronald E.,Narasimhan, Lakshmi S.,Holland, Debra R.,Rapundalo, Stephen T.,Edmunds, Jeremy J.
, p. 4089 - 4099 (2007/10/03)
Factor Xa (FXa) has materialized as a key enzyme for the intervention of the blood coagulation cascade and for the development of new antithrombotic agents. FXa is the lone enzyme responsible for the production of thrombin and therefore is an attractive t