24473-06-1

Basic information

• Product Name: 1-(4-Chlorophenoxy)-3,3-dimethyl-2-butanone
• Synonyms: 1-(4-Chlorophenoxy)-3,3-dimethyl-2-butanone;1-(4-chlorophenoxy)-3,3-dimethyl-butan-2-one;3,3-dimethyl-1-(4-chlorophenyl)butan-2-one;2-Butanone, 1-(4-chlorophenoxy)-3,3-dimethyl-;2-Butanone, 1-(p-chlorophenoxy)-3,3-dimethyl- (8ci);1-(4-chlorophenoxy)-3,3-dimethylbutan-2-one(WXC05061)
• CAS NO: 24473-06-1
• Molecular Formula: C₁₂H₁₅ClO₂
• Molecular Weight: 226.6993
• Mol File: 24473-06-1.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 304.1°C at 760 mmHg
• Flash Point: 117.3°C
• Appearance: /
• Density: 1.105g/cm³
• Vapor Pressure: 0.000896mmHg at 25°C
• Refractive Index: 1.506
• CAS DataBase Reference: 1-(4-Chlorophenoxy)-3,3-dimethyl-2-butanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Chlorophenoxy)-3,3-dimethyl-2-butanone(24473-06-1)
• EPA Substance Registry System: 1-(4-Chlorophenoxy)-3,3-dimethyl-2-butanone(24473-06-1)

Safety Data

• Hazardous Substances Data: 24473-06-1(Hazardous Substances Data)

Usage

Description

1-(4-Chlorophenoxy)-3,3-dimethyl-2-butanone, commonly known as phenoxybutanone, is a chemical compound characterized by its molecular formula C12H15ClO2. It is a clear, colorless liquid with a mild, floral odor, making it a popular choice as a flavoring agent and fragrance ingredient in the cosmetic and personal care industry. Phenoxybutanone is also utilized in the production of pharmaceuticals and serves as a solvent in the manufacturing of insecticides. However, it is crucial to handle this chemical with caution due to its potential to cause irritation to the skin, eyes, and respiratory system if not used properly.

Uses

Used in Cosmetic and Personal Care Industry:
1-(4-Chlorophenoxy)-3,3-dimethyl-2-butanone is used as a flavoring agent and fragrance ingredient for its sweet, floral scent, enhancing the sensory experience of various cosmetic and personal care products.
Used in Pharmaceutical Production:
In the pharmaceutical industry, 1-(4-Chlorophenoxy)-3,3-dimethyl-2-butanone is utilized in the manufacturing process, contributing to the development of different medicinal products.
Used in Insecticide Manufacturing:
1-(4-Chlorophenoxy)-3,3-dimethyl-2-butanone is employed as a solvent in the production of insecticides, playing a crucial role in the formulation and effectiveness of these products.

InChI:InChI=1/C12H15ClO2/c1-12(2,3)11(14)8-15-10-6-4-9(13)5-7-10/h4-7H,8H2,1-3H3

Upstream product

• 13547-70-1 1-chloro-3,3-dimethyl-butan-2-one 
• 106-48-9 4-chloro-phenol 
• 75-97-8 3,3-dimethyl-butan-2-one 
• 79989-30-3 1-(4-chlorophenoxy)-3,3-dimethyl-butan-2-ol 
• 17510-46-2 3,3-dimethyl-2-(trimethylsilyl)oxy-1-butene 
• 1193-00-6 sodium 4-chlorophenolate 
• 5469-26-1 1-Bromopinacolon 

Downstream Products

• 80443-61-4 2-(4-chlorophenoxy-methyl)-2-tert-butyl-oxirane 
• 70300-61-7 1-(4-chloro-phenoxy)-3,3-dimethyl-2-pyrimidin-5-yl-butan-2-ol 
• 57000-78-9 1-(4-chlorophenoxy)-1-chloro-3,3-dimethyl-butan-2-one 
• 79989-30-3 1-(4-chlorophenoxy)-3,3-dimethyl-butan-2-ol 

Relevant articles and documents

Synthesis of Vicinal Quaternary All-Carbon Centers via Acid-catalyzed Cycloisomerization of Neopentylic Epoxides

We report our studies on the development of a catalytic cycloisomerization of 2,2-disubstituted neopentylic epoxides to produce highly substituted tetralins and chromanes. Termination of the sequence occurs via Friedel-Crafts-type alkylation of the remote (hetero)arene linker. The transformation is efficiently promoted by sulfuric acid and proceeds best in 1,1,1,3,3,3-hexafluoroisopropanol (HFIP) as the solvent. Variation of the substitution pattern provided detailed insights into the migration tendencies and revealed a competing disproportionation pathway of dihydronaphthalenes.

Preparation method of climbazole

The invention discloses a preparation method of climbazole. According to the method, toluene, chloroetherketone, imidazole and a catalyst, serving as raw materials, react under 100 DEG C to 110 DEG Cfor 4 hours while the temperature is kept, and then the climbazole with the purity being up to 99 percent is prepared by methods, such as crystallization, purification, alkaline wash and recrystallization. Through a lot of experiments, the invention screens out the best climbazole preparation method, the whole process design is reasonable, the process is easy and efficient to operate, in particular, the best reaction conditions screened out, which include catalyst variety, reaction solvent, reaction temperature, reaction time and steps, such as crude reaction of methylbenzene and the climbazole, and alkaline wash thereof, can greatly increase reaction yield (up to 92 percent or above), side reaction is reduced, the reaction rate is increased, the production cost is greatly reduced, and therefore the preparation method of the climbazole has a good application prospect.

Phototransformation of triadimefon on glass and soil surfaces

Photodegradation of triadimefon has been studied on glass and soil surfaces. A number of photoproducts have been isolated and characterised by NMR, IR and MS. Photolysis resulted in considerable amounts of 1-(4- chlorophenoxymethyl)-1,2,4-triazole, 1-(4-chlorophenoxy)-2,2-dimethyl-1- (1,2,4-triazol-1-yl)propane, 1-(1,2,4-triazol-1-yl)-3,3-dimethylbutan-2-one and 1-(4-chlorophenoxy)-3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-ol. Rates of photodegradation on glass and soil surfaces under UV and sunlight followed first-order kinetics with a significant correlation coefficient. Photodegradation was greater on alluvial soil than on laterite soil.