24501-21-1 Usage
General Description
2,4-diamino-3-(nitro)pyridine is an organic compound with the chemical formula C5H6N4O2. It consists of a pyridine ring with amino groups at the 2 and 4 positions, and a nitro group at the 3 position. 2,4-diamino-3-(nitro)pyridine is commonly used in the synthesis of pharmaceuticals and agrochemicals, as well as in the manufacture of dyes and pigments. It is also used as a building block in organic chemistry, and its derivatives have shown potential in the treatment of certain diseases. 2,4-diamino-3-(nitro)pyridine is a versatile chemical that holds promise in a variety of applications due to its unique structure and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 24501-21-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,5,0 and 1 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 24501-21:
(7*2)+(6*4)+(5*5)+(4*0)+(3*1)+(2*2)+(1*1)=71
71 % 10 = 1
So 24501-21-1 is a valid CAS Registry Number.
24501-21-1Relevant articles and documents
Process Development and Multikilogram-Scale Synthesis of a TRPV1 Antagonist
Cleator, Ed,Scott, Jeremy P.,Avalle, Paulo,Bio, Matthew M.,Brewer, Sarah E.,Davies, Antony J.,Gibb, Andrew D.,Sheen, Faye J.,Stewart, Gavin W.,Wallace, Debra J.,Wilson., Robert D.
, p. 1561 - 1567 (2014/01/06)
The process development and multikilogram preparation of a TRPV1 antagonist, 1, is described. Pyrido[2,3-b]pyrazine 1 was prepared in a convergent manner by the coupling of two key fragments, glyoxal 2 and diamine 3. Glyoxal 2 was synthesized in six chemical steps in 20% overall yield, the key step being a challenging Grignard reaction to install the glyoxalate moiety. Diamine 3 was also prepared in six chemical steps in 46% overall yield, exploiting a regioselective nucleophilic aromatic substitution to obtain the key nitrodiamine intermediate 19.
