24559-80-6

Basic information

• Product Name: dimethyl (Z)-N-(4-methylphenyl)aminofumarate
• Synonyms: dimethyl (Z)-N-(4-methylphenyl)aminofumarate
• CAS NO: 24559-80-6
• Molecular Weight: 249.266
• Mol File: 24559-80-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: dimethyl (Z)-N-(4-methylphenyl)aminofumarate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl (Z)-N-(4-methylphenyl)aminofumarate(24559-80-6)
• EPA Substance Registry System: dimethyl (Z)-N-(4-methylphenyl)aminofumarate(24559-80-6)

Safety Data

• Hazardous Substances Data: 24559-80-6(Hazardous Substances Data)

Upstream product

• 106-49-0 p-toluidine 
• 762-42-5 dimethyl acetylenedicarboxylate 

Downstream Products

• 607692-48-8 1-(2-hydroxyethyl)-3-(p-tolylamino)pyrrole-2,5-dione 
• 1147844-83-4 dimethyl 6-(4-nitrophenyl)-2-oxo-3-(4-tolyl)-1,2,3,6-tetrahydropyrimidine-4,5-dicarboxylate 
• 1238054-72-2 dimethyl 3-(4-methylphenyl)-6-oxo-2-phenyl-2-trifluoromethyl-1,2,3,6-tetrahydropyrimidine-4,5-dicarboxylate 
• 1238054-63-1 dimethyl 6-(3-bromophenyl)-2-oxo-3-(4-tolyl)-1,2,3,6-tetrahydropyrimidine-4,5-dicarboxylate 

Relevant articles and documents

CuCl2-mediated reaction of [60]fullerene with amines in the presence or absence of dimethyl acetylenedicarboxylate: Preparation of fulleropyrroline or aziridinofullerene derivatives

The CuCl2-mediated three-component reaction of C60 with amines and dimethyl acetylenedicarboxylate afforded the fulleropyrrolines in moderate yields. Furthermore, the CuCl2-mediated oxidative [2 + 1] reaction of C60 with aromatic amines bearing a strong electron-withdrawing group provided the aziridinofullerenes and the selective cis-1-bisaziridinofullerenes.

Synthesis of 1-alkyl-3-arylamino-pyrrole-2,5-diones

Reaction of 1-alkyl-3-alkylaminopyrrole-2,5-diones with primary arylamine hydrochlorides in methanol or DMSO gives 1-alkyl-3-arylaminopyrrole-2,5-diones which could also be obtained from the reaction of arylaminofumarates with primary aliphatic amines.