24572-48-3

Basic information

• Product Name: Benzene, 1-fluoro-4-(tribromomethyl)-
• CAS NO: 24572-48-3
• Molecular Formula: C7H4Br3F
• Molecular Weight: 346.819
• Mol File: 24572-48-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzene, 1-fluoro-4-(tribromomethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-fluoro-4-(tribromomethyl)-(24572-48-3)
• EPA Substance Registry System: Benzene, 1-fluoro-4-(tribromomethyl)-(24572-48-3)

Safety Data

• Hazardous Substances Data: 24572-48-3(Hazardous Substances Data)

Upstream product

• 352-32-9 p-fluorotoluene 
• 402-44-8 4-Fluorobenzotrifluoride 

Downstream Products

• 24572-43-8 p-FC₆H₄C(SCF₃)3 
• 1208259-07-7 2-(4-fluorophenyl)-quinazoline 

Relevant articles and documents

Preparation method of diaryl acetylene compounds

The invention relates to preparation of an organic compound, and aims to provide a preparation method of diaryl acetylene compounds. The preparation method includes steps of adding associated tribromomethylarene compound and copper in a reactor to perform deoxidizing treatment; dissolving polyamine in a proper amount of anhydrous and oxygen-free solvent, and then adding to the reactor; performingcoupling reaction at 30-80DEG C for 3-12 hours; separating and purifying to obtain diaryl acetylene compounds. The preparation is gentle in synthesis condition and the reaction has good compatibilityto different functional groups; the raw material associated tribromomethylarene compound is convenient to compound and has different substituent groups and variable structure; by adopting one raw material, high-quality product can be obtained through simple treatment, and the output is high; by adopting two different raw materials, the asymmetrical diaryl acetylene compound can be prepared.

Catalytic halodefluorination of aliphatic carbon-fluorine bonds

A variety of halosilanes, in conjunction with aluminum catalysts, convert fluorocarbons into higher halocarbons. Bromination and iodination of fluorocarbons are more effective than chlorination in terms of yield and activity. The mechanism for the reaction is investigated utilizing experimental and computational evidence and preliminary results suggest an alternate mechanism to that reported for the related hydrodefluorination reaction.