24591-15-9

Basic information

• Product Name: N-(4-chloro-2-nitrophenyl)-N-(4-chlorophenyl)amine
• Synonyms: N-(4-chloro-2-nitrophenyl)-N-(4-chlorophenyl)amine
• CAS NO: 24591-15-9
• Molecular Weight: 283.114
• Mol File: 24591-15-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-chloro-2-nitrophenyl)-N-(4-chlorophenyl)amine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-chloro-2-nitrophenyl)-N-(4-chlorophenyl)amine(24591-15-9)
• EPA Substance Registry System: N-(4-chloro-2-nitrophenyl)-N-(4-chlorophenyl)amine(24591-15-9)

Safety Data

• Hazardous Substances Data: 24591-15-9(Hazardous Substances Data)

Upstream product

• 106-47-8 4-chloro-aniline 
• 89-61-2 2,5-dichloronitrobenzene 

Downstream Products

• 17274-71-4 3,6-dichloro-N-benzoylcarbazole 
• 29328-99-2 5,4'-Dichlor-1-phenylbenzotriazol 
• 23648-87-5 4-chloro-N¹-(4-chloro-phenyl)-o-phenylenediamine 

Relevant articles and documents

Synthesis and biological evaluation of novel pyrazole carboxamide with diarylamine-modi?ed scaffold as potent antifungal agents

Twenty-seven novel pyrazole carboxamides with diarylamine-modi?ed scaffold were designed, synthesized and characterized in detail via 1H NMR, 13C NMR, IR and ESI-HRMS. Preliminary bioassays showed that some of the target compounds exhibited good antifungal activity against Rhizoctonia solani, Rhizoctonia cerealis and Sclerotinia sclerotiorum. Among them, compound 9c-7 exhibited the highest antifungal activities against R. solani, R. cerealis and S. sclerotiorum in vitro with IC50 values of 0.013, 1.608 and 1.874?μg/mL, respectively. Notably, compound 9c-7 still presented the highest fungicidal activities against R. solani in vivo with an IC50 value of 22.21?μg/mL. Molecular docking simulation results reveal that compound 9c-7 binds well to the hydrophobic pockets of the receptor protein succinate dehydrogenase. This study suggests that compound 9c-7 could act as a potential fungicide to be used for further optimization.