24596-18-7 Usage
Description
4-Chloro-2,6-Dimethylaniline is an organic compound with the molecular formula C8H10ClN. It is characterized by the presence of a chlorine atom at the 4-position, and two methyl groups at the 2 and 6 positions of the aniline molecule. 4-Chloro-2,6-Dimethylaniline is known for its reactivity and is commonly used as a substrate in various chemical reactions.
Uses
Used in Chemical Synthesis:
4-Chloro-2,6-Dimethylaniline is used as a substrate in palladium-catalyzed cyanations of aryl chlorides. This application is significant because it allows for the formation of new chemical bonds and the synthesis of various organic compounds that can be utilized in different industries.
In the Pharmaceutical Industry:
4-Chloro-2,6-Dimethylaniline is used as a building block for the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable component in the development of new drugs and medications.
In the Dye and Pigment Industry:
4-Chloro-2,6-Dimethylaniline is used as an intermediate in the production of dyes and pigments. Its chemical properties contribute to the color and stability of these products, making it an essential component in this industry.
In the Agrochemical Industry:
4-Chloro-2,6-Dimethylaniline is used in the synthesis of agrochemicals, such as pesticides and herbicides. Its role in these applications is to provide the necessary chemical structure for the active ingredients to be effective in controlling pests and unwanted plant growth.
In the Polymer Industry:
4-Chloro-2,6-Dimethylaniline is used as a monomer in the production of polymers. Its incorporation into the polymer chain can enhance the properties of the final product, such as strength, durability, and resistance to environmental factors.
Check Digit Verification of cas no
The CAS Registry Mumber 24596-18-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,5,9 and 6 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 24596-18:
(7*2)+(6*4)+(5*5)+(4*9)+(3*6)+(2*1)+(1*8)=127
127 % 10 = 7
So 24596-18-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H10ClN/c1-5-3-7(9)4-6(2)8(5)10/h3-4H,10H2,1-2H3
24596-18-7Relevant articles and documents
Recyclable ionic liquid iodinating reagent for solvent free, regioselective iodination of activated aromatic and heteroaromatic amines
Deshmukh, Amarsinh,Gore, Babasaheb,Thulasiram, Hirekodathakallu V.,Swamy, Vincent P.
, p. 88311 - 88315 (2015/11/09)
This article describes a simple, efficient method for iodination of activated aromatic and heteroaromatic amines using recyclable 1-butyl-3-methylpyridinium dichloroiodate (BMPDCI) as an ionic liquid iodinating reagent, in the absence of any solvent. The main advantages are a simple efficient procedure, good yields and no need for any base/toxic heavy metals, or oxidizing agents. The ionic liquid was recovered and recycled in five subsequent reactions, without much loss of activity. This method was applied for the synthesis of the antiprotozoal drug iodoquinol and the antifungal drug clioquinol.
Halide ion trapping of nitrenium ions formed in the Bamberger rearrangement of N-arylhydroxylamines. Lifetime of the parent phenylnitrenium ion in water
Fishbein,McClelland
, p. 1321 - 1328 (2007/10/03)
The data of p-aminophenol, the product of Bamberger rearrangement, Were analyzed by a mechanism involving rate-limiting formation of the appropriate arylnitrenium ion followed by product-determining steps in involving trapping by the solvent or by the added halide. The possibility that a portion of the halide-trapped products were derived from a pre-association mechanism was also include. Kinetic analyses then produced kBr:kw and kCl:kw ratios for two limiting cases, one involving pre-association with an equilibrium constant Kas = 0.3, and one ignoring pre-association. From an azide:water ratio (kAz:kw) previously determined for the 2,6-dimethylphenylnitrenium, kBr was concluded to lie in the range (4-5) × 109 M-1 s-1 for all of the nitrenium ions of this study. This range for kBr then led to kw values of (1-2) × 109 s-1 (2,5-Me2), (2-3) × 109 s-1 (2-Me), and (4-8) × 109 s-1 (parent and 2-Cl), where the ranges reflect uncertainties in the exact value of kBr and in the contribution from pre-association. The lifetime of the parent phenylnitrenium ion in water at one molar ionic strength is concluded to lie in the range 125-250 ps.