2460-59-5

Basic information

• Product Name: 3,5-DINITROSALICYLALDEHYDE
• Synonyms: 2-HYDROXY-3,5-DINITROBENZALDEHYDE;3,5-DINITRO-2-HYDROXYBENZALDEHYDE;3,5-DINITROSALICYLALDEHYDE;Benzaldehyde, 2-hydroxy-3,5-dinitro-;2-HYDROXY-3,5-DINITROBENZALDEHYDE 95%;3,5-Dinitrosalicylaldehyde 97%
• CAS NO: 2460-59-5
• Molecular Formula: C₇H₄N₂O₆
• Molecular Weight: 212.12
• EINECS: 219-551-5
• Product Categories: Aromatic Aldehydes & Derivatives (substituted);Aldehydes;C7;Carbonyl Compounds
• Mol File: 2460-59-5.mol
• Article Data: 5

Chemical Properties

• Melting Point: 68-70 °C(lit.)
• Boiling Point: 301.5 °C at 760 mmHg
• Flash Point: 133.3 °C
• Appearance: /
• Density: 1.721 g/cm³
• Vapor Pressure: 0.000585mmHg at 25°C
• PKA: 2.06±0.44(Predicted)
• Water Solubility: Soluble in water, 0.6 g/100 mL (18°C).
• Sensitive: Air Sensitive
• BRN: 1121900
• CAS DataBase Reference: 3,5-DINITROSALICYLALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DINITROSALICYLALDEHYDE(2460-59-5)
• EPA Substance Registry System: 3,5-DINITROSALICYLALDEHYDE(2460-59-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• RIDADR: 2811
• WGK Germany: 3
• TSCA: Yes
• HazardClass: 6.1(b)
• PackingGroup: II
• Hazardous Substances Data: 2460-59-5(Hazardous Substances Data)

Usage

Description

3,5-Dinitrosalicylaldehyde is an organic compound with the chemical formula C7H4N2O5. It is a yellow crystalline solid that is soluble in water and ethanol. 3,5-DINITROSALICYLALDEHYDE is known for its reactivity and is often used as a building block in the synthesis of various organic compounds.

Uses

Used in Chemical Synthesis:
3,5-Dinitrosalicylaldehyde is used as a key intermediate in the production of 3-(2-hydroxy-3,5-dinitro-phenyl)-propenal with acetaldehyde. 3,5-DINITROSALICYLALDEHYDE serves as an important building block for the synthesis of various organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3,5-dinitrosalicylaldehyde is used in the preparation of salicyldimine ligands via Schiff base condensation with allyl-substituted aniline. These ligands are essential in the development of new drugs and pharmaceutical compounds.
Used in Chemical Research:
3,5-Dinitrosalicylaldehyde is also utilized in the synthesis of 3-hydroxycoumarins, which are a class of organic compounds with potential applications in various fields, including pharmaceuticals and agrochemicals.
Used in Analytical Chemistry:
3,5-DINITROSALICYLALDEHYDE is employed as a chromogenic proteinase substrate, which is crucial in the development of assays and tests for the detection and quantification of proteolytic enzymes.
Used in Coordination Chemistry:
3,5-Dinitrosalicylaldehyde is used in the preparation of ruthenium(II) chiral Schiff base complexes, which are essential in the field of coordination chemistry and have potential applications in catalysis and as chiral catalysts.

InChI:InChI=1/C7H4N2O6/c10-3-4-1-5(8(12)13)2-6(7(4)11)9(14)15/h1-3,11H/p-1

Upstream product

• 90-02-8 salicylaldehyde 
• 67-68-5 dimethyl sulfoxide 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 7697-37-2 nitric acid 
• 64-19-7 acetic acid 
• 89-95-2 2-methyl-benzyl alcohol 
• 97-51-8 5-Nitrosalicylaldehyde 
• 88-85-7 dinoseb 

Downstream Products

• 123541-15-1 C₈H₈N₆O₆*C₇H₈O₃S 
• 20200-64-0 6,8-dinitro-1',3',3'-trimethylspiro<2H-1-benzopyran-2,2'-indoline> 
• 99833-61-1 C₁₉H₁₅N₃O₇ 
• 92708-85-5 3,5-dinitro-2-hydroxycinnamaldehyde 
• 609-99-4 3,5-dinitrosalicylic acid 
• 88-89-1 2,4,6-Trinitrophenol 

Relevant articles and documents

Photocatalytic activity of TiO2 supported SiO2-Al2O3 aerogels prepared from industrial fly ash

A ternary composite of TiO2 and a SiO2-Al2O3 aerogel with good photocatalytic activity was prepared by a simple sol-gel method with TiO2 nanoparticles and SiO2-Al2O3 aerogels derived from industrial fly ash. The structural features of the TiO2/SiO2-Al2O3 aerogel composite were investigated by X-ray powder diffraction, Fourier transform infrared spectroscopy, transmission electron microscopy, gas adsorption measurements and diffuse reflectance UV-visible spectroscopy. The optimal conditions for photocatalytic degradation of 2-sec-butyl-4,6-dinitrophenol (DNBP), included an initial DNBP concentration of 0.167 mmol/L at pH = 4.86 with a catalyst concentration of 6 g/L, under visible light irradiation for 5 h. A plausible mechanism is proposed for the photocatalytic degradation of DNBP. Our composite showed higher photocatalytic activity for DNBP degradation than that of pure TiO2. This indicates that this material can serve as an efficient photocatalyst for degradation of hazardous organic pollutants in wastewater.

Cold microwave chemistry: synthesis using pre-cooled reagents

A novel experimental procedure for chemical reactions has been devised that involves mixing and then freezing the reagents (organic solvent-free) to a sub-zero temperature such as -30 °C. This frozen mixture is exposed to microwave irradiation for a brief period of time. The use of pre-cooled reagents may give a single product not obtained by traditional microwave irradiation at room temperature. Interestingly, such a product may provide information about mechanisms by identifying the first step of a multiple step reaction.

Method for producing optically active salicylaldimine copper complex

There is provided a method for producing an optically active salicylaldimine copper complex, which method is characterized in that an optically active amino alcohol compound represented by the following formula (1) is reacted with copper hydroxide (II) in an organic solvent. wherein R1 and R2 which are the same or different, each represent lower alkyl groups and the like which may be substituted, X1 and X2 which are the same or different, each represent a hydrogen atom, lower alkyl groups and the like, and the symbol * designates an asymmetric carbon atom.