2461-80-5

Basic information

• Product Name: BIS(BENZOYLMETHYL) SULFIDE
• Synonyms: BIS(BENZOYLMETHYL) SULFIDE;Bis(2-phenyl-2-oxoethyl) sulfide;Diphenacyl sulfide;α,α'-Thiobisacetophenone;2-(2-oxo-2-phenyl-ethyl)sulfanyl-1-phenyl-ethanone;2-(2-oxo-2-phenylethyl)sulfanyl-1-phenylethanone;2-[(2-keto-2-phenyl-ethyl)thio]-1-phenyl-ethanone;2,2'-Thiobis(1-phenylethanone)
• CAS NO: 2461-80-5
• Molecular Formula: C₁₆H₁₄O₂S
• Molecular Weight: 270.35
• Mol File: 2461-80-5.mol
• Article Data: 21

Chemical Properties

• Melting Point: 77 °C
• Boiling Point: 434.5 °C at 760 mmHg
• Flash Point: 188.8 °C
• Appearance: /
• Density: 1.189 g/cm³
• CAS DataBase Reference: BIS(BENZOYLMETHYL) SULFIDE(CAS DataBase Reference)
• NIST Chemistry Reference: BIS(BENZOYLMETHYL) SULFIDE(2461-80-5)
• EPA Substance Registry System: BIS(BENZOYLMETHYL) SULFIDE(2461-80-5)

Safety Data

• Hazardous Substances Data: 2461-80-5(Hazardous Substances Data)

Usage

General Description

Bis(benzoylmethyl) sulfide is a chemical compound with the formula (C6H5COCH2)2S. It is commonly used as a crosslinking agent in chemical synthesis, particularly in the production of polymers and resins. It is also used as a photoinitiator in the production of photopolymers and as a catalyst in organic reactions. Bis(benzoylmethyl) sulfide has a low volatility and high thermal stability, making it a suitable ingredient in many industrial applications. It is considered to be a skin irritant and should be handled with care and disposed of according to proper safety protocols.

Upstream product

• 13442-04-1 2,7-dihydro-3,6-diphenyl-1,4,5-thiadiazepine 
• 60-29-7 diethyl ether 
• 7783-06-4 hydrogen sulfide 
• 7732-18-5 water 
• 70-11-1 α-bromoacetophenone 
• 7257-94-5 1-phenyl-2-(p-tolylsulfonyloxy)ethanone 
• 53392-49-7 phenacyl thioacetate 
• 2462-02-4 2-mercaptoacetophenone 
• 98-86-2 acetophenone 
• 31410-18-1 benzyl-methyl-phenacyl sulfonium ; bromide 
• 2408-88-0 2-benzylsulfanyl-1-phenylethanone 
• 64-17-5 ethanol 
• 532-27-4 1-chloroacetophenone 
• 32188-99-1 2-phenacylthioimidazoline 

Downstream Products

• 19221-12-6 3,5-Diphenyl-2H-1,4-thiazine 
• 3708-08-5 Diphenacyl sulfone 
• 13442-04-1 2,7-dihydro-3,6-diphenyl-1,4,5-thiadiazepine 
• 32120-82-4 bis(benzoylmethyl) sulfoxide 
• 55716-17-1 diphenacyl sulfid-anti-monohydrazone 
• 148638-23-7 (Z,Z)-2,2'-thiobis(1,3-diphenylprop-2-en-1-one) 
• 71764-42-6 1,2,3,4,9,9a-hexahydro-6,9a-diphenyl-1H-pyrimido<2,1-c><1,4>thiazine 
• 242133-10-4 (Z,Z)-2,2'-thiobis(3-(4-chlorophenyl)-1-phenylprop-2-en-1-one) 
• 4217-65-6 (R,S)-2,3-diphenylbutane-2,3-diol 
• 100990-36-1 cis-3,4-dihydroxy-3,4-diphenylthiolane 1,1-dioxide 
• 14006-54-3 3-chloro-1-benzothiophen-2-carbaldehyde 

Relevant articles and documents

Continuous Flow Synthesis of 2H-Thiopyrans via thia-Diels–Alder Reactions of Photochemically Generated Thioaldehydes

Herein, we report a novel protocol for the photochemical generation of thioaldehydes in a continuous flow process which were in situ reacted with electron rich 1,3-butadienes in thia-Diels–Alder reactions. A broad range of 3,6-dihydro-2H-thiopyrans were formed as products in much higher yields and productivities as compared to classical batch processes. Moreover, greatly reduced reaction times and a facile large-scale preparation of products were achieved by fully exploiting the advantages of continuous flow technology.

Synthesis of Thioethers Using Triethylamine-Activated Phosphorus Decasulfide (P410

The synthesis of thioethers in excellent yields was achieved under mild conditions via the displacement reaction of halogens by sulfur. The cross-reaction of 2-(α-bromoacetyl)thiophene with triethylamine-activated phosphorus decasulfide (Et3N-P2S5) was elaborated by utilizing DFT calculations.

Stereoselective synthesis of cis-2,6-disubstituted morpholines and 1,4-oxathianes by intramolecular reductive etherification of 1,5-diketones

A simple and efficient, Lewis acid catalysed reductive etherification strategy for the stereoselective synthesis of cis-2,6- disubstituted morpholines and 1,4-oxathianes starting from readily available 1,5-diketones has been developed. The strategy is used in the total synthesis of morpholine-based natural products (±)-chelonin A and formal total synthesis of (±)-chelonin C.