24622-32-0

Basic information

• Product Name: 2-Benzothiazolamine,N-(2-methylpropyl)-(9CI)
• Synonyms: 2-Benzothiazolamine,N-(2-methylpropyl)-(9CI);N-(2-Methylpropyl)-2-benzothiazolamine;N-(2-methylpropyl)-1,3-benzothiazol-2-amine
• CAS NO: 24622-32-0
• Molecular Formula: C₁₁H₁₄N₂S
• Molecular Weight: 206.31
• Product Categories: BENZOTHIAZOLE
• Mol File: 24622-32-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 306.9 °C at 760 mmHg
• Flash Point: 139.4 °C
• Appearance: /
• Density: 1.174 g/cm³
• Vapor Pressure: 0.000748mmHg at 25°C
• Refractive Index: 1.649
• CAS DataBase Reference: 2-Benzothiazolamine,N-(2-methylpropyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Benzothiazolamine,N-(2-methylpropyl)-(9CI)(24622-32-0)
• EPA Substance Registry System: 2-Benzothiazolamine,N-(2-methylpropyl)-(9CI)(24622-32-0)

Safety Data

• Hazardous Substances Data: 24622-32-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C11H14N2S/c1-8(2)7-12-11-13-9-5-3-4-6-10(9)14-11/h3-6,8H,7H2,1-2H3,(H,12,13)

Upstream product

• 16275-53-9 1-(2-methylpropyl)-3-phenylthiourea 
• 3028-04-4 N-(benzo[d]thiazol-2-yl)isobutyramide 
• 136-95-8 2-amino-benzthiazole 
• 615-20-3 2-chlorobenzo[d][1,3]thiazole 
• 78-81-9 isobutylamine 

Downstream Products

• 77427-26-0 C₁₄H₁₄N₂O₂S 

Relevant articles and documents

Convenient and reliable routes towards 2-aminothiazoles: Palladium-catalyzed versus copper-catalyzed aminations of halothiazoles

Two efficient methods for the amination of 2-halothiazoles are presented here. A first protocol requires a Pd/L system. Several 2-aminothiazoles were synthesized under optimized conditions and isolated in good yields. The first palladium-catalyzed C-N coupling reactions between 2-halothiazoles and primary alkylamines are presented. In a second part, ligand-free copper-catalyzed aminations of 2-halothiazoles by alkylamines and aniline in a green solvent have been developed. The protocol is very effective for primary and secondary amines and perfectly tolerates the presence of another halide moiety on the 2-halothiazole. The reaction occurs under the assistance of microwave irradiation, which drastically decreases the reaction time. The reaction leads to the formation of 2-aminothiazoles, key molecules in pharmaceutical research. Copyright

Benz-fused mesoionic xanthine analogues as inhibitors of cyclic-AMP phosphodiesterase

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