24653-82-5

Basic information

• Product Name: Methanediol, (2,6-dichlorophenyl)-, diacetate
• CAS NO: 24653-82-5
• Molecular Formula: C11H10Cl2O4
• Molecular Weight: 277.104
• Mol File: 24653-82-5.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: Methanediol, (2,6-dichlorophenyl)-, diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: Methanediol, (2,6-dichlorophenyl)-, diacetate(24653-82-5)
• EPA Substance Registry System: Methanediol, (2,6-dichlorophenyl)-, diacetate(24653-82-5)

Safety Data

• Hazardous Substances Data: 24653-82-5(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 83-38-5 2,6-dichlorobenzaldehyde 
• 127-09-3 sodium acetate 

Downstream Products

• 6575-25-3 1,3-dichloro-2-ethynyl-benzene 
• 24653-87-0 2,3-dibromo-3-(2,6-dichloro-phenyl)-propionic acid 
• 24653-88-1 (2,6-dichloro-phenyl)-propiolic acid 
• 83-38-5 2,6-dichlorobenzaldehyde 
• 20595-49-7 (2E)-3-(2,6-dichlorophenyl)prop-2-enoic acid 

Relevant articles and documents

(NH4)3PW12O40 as an efficient and reusable catalyst for the synthesis and deprotection of 1,1-diacetates

An efficient method for the synthesis of 1,1-diacetates (acylals) from different aldehydes in the presence of (NH4)3PW12O40 and acetic anhydride under solvent-free conditions at ambient temperature is achieved. Selective conversion of aldehydes was observed in the presence of ketones. The deprotection of acylals has also been achieved using (NH4)3PW12O40 in methanol. The catalyst was found to possess good activity and considerable level of reusability. Copyright Taylor & Francis Group, LLC.

Solvent-free Chemoselective Synthesis of 1,1-diacetates Catalyzed by Iron Zirconium Phosphate

In the present study, a mild, rapid, and efficient method for the protection of aldehydes with acetic anhydride (AA) in the presence of iron zirconium phosphate (ZPFe), at room temperature is reported. Selective conversion of aldehydes was observed in the presence of ketones. Under these conditions, different aldehydes bearing electron-withdrawing and electron-donating substituents were reacted with AA and the corresponding 1,1-diacetates (acylals) were obtained in high to excellent yields. The steric and electronic properties of the different substrates had a significant influence on the reaction conditions. Also, the deprotection of 1,1-diacetates has been achieved using this catalyst in water. The catalyst was characterized by several physico-chemical techniques. It was recovered easily from the reaction mixture, regenerated, and reused at least 7 times without significant loss in catalytic activity. This protocol has the advantages of easy availability, stability, reusability of the eco-friendly catalyst, chemoselectivity, simple experimental and work-up procedure, solvent-free conditions and only a stoichiometric amount of AA is needed.

A highly efficient solvent-free acetalization of aldehydes to 1,1-diacetates catalyzed by SiO2-Pr-SO3H

1,1-Diacetates are prepared in excellent yields from aldehydes and acetic anhydride under solvent-free conditions at room temperature in short reaction times using catalytic amount of sulfonic acid functionalized silica (SiO 2-Pr-SO3H) which could be easily handled and removed from the mixture of reaction.