2469-34-3 Usage
Description
SENEGENIN is a natural compound derived from various plant sources, including P. tenuifolia. It is a triterpenoid sapogenin with diverse biological activities, such as antioxidant, anti-inflammatory, and neuroprotective properties. SENEGENIN has been found to inhibit the production of IL-1β and reactive oxygen species (ROS) in toxin-induced cell models of Parkinson's disease, making it a promising candidate for pharmaceutical applications.
Uses
Used in Pharmaceutical Industry:
SENEGENIN is used as an anti-oxidative and anti-inflammatory agent for its ability to inhibit IL-1β and ROS production in toxin-induced cell models of Parkinson's disease. This makes it a potential candidate for the development of treatments targeting neurodegenerative diseases.
Used in Neuroprotective Applications:
SENEGENIN is used as a neuroprotective agent for its ability to decrease NLRP3 inflammasome activation and prevent dopaminergic neuronal degeneration in the mouse substantia nigra pars compacta in an MPTP-induced model of Parkinson's disease. This suggests its potential use in protecting neurons and improving outcomes in patients with neurodegenerative conditions.
Used in Anti-Inflammatory Applications:
SENEGENIN is used as an anti-inflammatory agent for its capacity to reduce lung edema and the levels of IL-1β and TNF-α in bronchoalveolar lavage fluid (BALF) in a mouse model of intranasal S. aureus-induced pneumonia. This indicates its potential utility in treating inflammatory conditions and infections.
Check Digit Verification of cas no
The CAS Registry Mumber 2469-34-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,4,6 and 9 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2469-34:
(6*2)+(5*4)+(4*6)+(3*9)+(2*3)+(1*4)=93
93 % 10 = 3
So 2469-34-3 is a valid CAS Registry Number.
InChI:InChI=1/C30H45ClO6/c1-26(2)10-11-30(25(36)37)9-6-17-22(18(30)13-26)16(15-31)12-21-27(17,3)8-7-20-28(21,4)14-19(32)23(33)29(20,5)24(34)35/h16,18-21,23,32-33H,6-15H2,1-5H3,(H,34,35)(H,36,37)
