24700-81-0Relevant articles and documents
Novel tocopheryl compounds. Part 15: One-pot formation of furotocopheryl derivatives
Adelw?hrer, Christian,Rosenau, Thomas,Binder, Wolfgang H.,Kosma, Paul
, p. 3231 - 3235 (2003)
Reaction of tocopheryl bromide 2a or chromanyl bromide 2b with triphenyl phosphine produced phosphomium salt intermediates (3a-b), which further reacted with acyl chlorides to novel furotocopherol compounds 4-11 in good yields. The cyclization proceeded according to a two step esterification-Wittig mechanism. Similarly, furotocopheryl dimer 12 was prepared starting from oxalyl chloride. The coupling of tocopheryl phosphonium salt 3a onto modified polystyrene provided a new, vitamin E-loaded resin.
Diversity-oriented synthesis of furo[3,2-f]chromanes with antimycobacterial activity
Alvey, Luke,Prado, Soizic,Saint-Joanis, Brigitte,Michel, Sylvie,Koch, Michel,Cole, Stewart T.,Tillequin, Francois,Janin, Yves L.
experimental part, p. 2497 - 2505 (2009/09/30)
We previously reported the synthesis and the antimycobacterial activity of 4-(7,7-dimethyl-7H-furo[3,2-f]chromen-2-yl)pyridine. From this result, we sought to design simple synthetic accesses to related structures allowing the preparation of a diverse set
