247069-27-8 Usage
Description
3,5-Difluoropyridine-2,6-diamine is an organic compound with the molecular formula C5H5F2N3. It is characterized by the presence of two fluorine atoms at the 3rd and 5th positions of the pyridine ring, and two amine groups at the 2nd and 6th positions. 3,5-Difluoropyridine-2,6-diamine is slightly soluble in water and is utilized as a reagent in the synthesis of various pharmaceutical compounds.
Uses
Used in Pharmaceutical Synthesis:
3,5-Difluoropyridine-2,6-diamine is used as a reagent for the synthesis of 1-(6-amino-3,5-difluoropyridin-2-yl)fluoroquinolone, a compound with antimycobacterial and antibacterial activity. This application is significant in the development of new drugs to combat resistant strains of tuberculosis and other bacterial infections.
Used in Chemical Research:
Due to its unique structure and reactivity, 3,5-Difluoropyridine-2,6-diamine can also be employed in chemical research for the exploration of novel synthetic pathways and the development of new compounds with potential applications in various fields, including material science, agrochemistry, and pharmaceuticals.
Check Digit Verification of cas no
The CAS Registry Mumber 247069-27-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,7,0,6 and 9 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 247069-27:
(8*2)+(7*4)+(6*7)+(5*0)+(4*6)+(3*9)+(2*2)+(1*7)=148
148 % 10 = 8
So 247069-27-8 is a valid CAS Registry Number.
InChI:InChI=1/C5H5F2N3/c6-2-1-3(7)5(9)10-4(2)8/h1H,(H4,8,9,10)
247069-27-8Relevant articles and documents
Direct di- and triamination of polyfluoropyridines in anhydrous ammonia
Kusov, Soltan Z.,Rodionov, Vladimir I.,Vaganova, Tamara A.,Shundrina, Inna K.,Malykhin, Evgenij V.
, p. 461 - 465 (2009)
Aminodefluorination of polyfluoropyridines (pentafluoro-, 3,5-dichlorotrifluoro-, 3- and 4-chlorotetrafluoro-, 2,3,5,6- and 2,3,4,6-tetrafluoro-, 3-chloro-2,4,6-trifluoro-, and 2,4,6-trifluoropyridine) in anhydrous ammonia has been investigated. Temperatu
Method for preparing 2,6-diamino-3,5-difluoropyridine
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, (2019/10/01)
The invention discloses a method for preparing an intermediate of an anti-infectious new drug Delafloxacin, i.e., 2,6-diamino-3,5-difluoropyridine. The method comprises the steps of taking 2,3,5,6-tetrafluoropyridine as a raw material, and carrying out a
PREPARATION OF PYRIDONECARBOXYLIC ACID ANTIBACTERIALS
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Page/Page column 14, (2008/06/13)
A process for making 1-(6-amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid, and therapeutically acceptable salts thereof, and intermediates used in the process are disclosed.
