247083-17-6Relevant articles and documents
Pd(0) amination of benzimidazoles as an efficient method towards new (benzimidazolyl)piperazines with high affinity for the 5-HT(1A) receptor
López-Rodríguez, María L.,Benhamú, Bellinda,Ayala, David,Rominguera, J. Luis,Murcia, Marta,Ramos, José A.,Viso, Alma
, p. 3245 - 3253 (2007/10/03)
New (benzimidazolyl)amines have been synthesized from 4- and 6- bromobenzimidazole derivatives via palladium-mediated amination reactions. Among them, (benzimidazol-4(7)-yl)piperazine derivatives have been shown to be a new family of high affinity 5-HT(1A) receptor ligands. (C) 2000 Elsevier Science Ltd.