247088-44-4

Basic information

• Product Name: BOC-TYR(ET)-OH
• Synonyms: BOC-PHE(4-OET)-OH;BOC-TYR-OET;BOC-TYROSINE(ET)-OH;N-ALPHA-T-BUTOXYCARBONYL-O-ETHYL-L-TYROSINE;N-ALPHA-T-BOC-O-ETHYL-L-TYROSINE;N-(TERT-BUTOXYCARBONYL)-O-ETHYLTYROSINE;N-Boc-O-ethyl-DL-tyrosine
• CAS NO: 247088-44-4
• Molecular Formula: C16H23NO5
• Molecular Weight: 309.36
• Mol File: 247088-44-4.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 472.7 °C at 760 mmHg
• Flash Point: 239.7 °C
• Appearance: /
• Density: 1.149 g/cm³
• CAS DataBase Reference: BOC-TYR(ET)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-TYR(ET)-OH(247088-44-4)
• EPA Substance Registry System: BOC-TYR(ET)-OH(247088-44-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 247088-44-4(Hazardous Substances Data)

Usage

General Description

BOC-TYR(ET)-OH is a chemical compound with the formula C20H25NO7. It is a derivative of the amino acid tyrosine, with a tert-butoxycarbonyl (BOC) group protecting the amine group and an ethyl (ET) group attached to the hydroxyl group. BOC-TYR(ET)-OH is commonly used as a building block for the synthesis of peptides and proteins in organic chemistry. The BOC protecting group can be removed under mild acidic conditions, allowing the tyrosine residue to participate in peptide bond formation. BOC-TYR(ET)-OH is widely used in the pharmaceutical industry for the production of peptides and peptide-based drugs.

Upstream product

• 58632-95-4 2-(tert-Butoxycarbonyloxyimino)-2-phenylacetonitrile 
• 32795-52-1 β-p-ethoxyphenyl-β-alanine 
• 60-18-4 L-tyrosine 
• 64-67-5 diethyl sulfate 
• 3978-80-1 Boc-Tyr-OH 
• 3417-91-2 L-tyrosine methyl ester HCl 
• 4326-36-7 (S)-N-(tert-butoxycarbonyl)tyrosine methyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 92507-32-9 O-ethyl-N-tert-butoxycarbonyl-L-tyrosine methyl ester 
• 3728-20-9 D-tyrosine methylester hydrochloride 
• 76757-90-9 N-(tert-butoxycarbonyl)-D-tyrosine methyl ester 
• 556-02-5 tyrosine 
• 92507-32-9 (R)-2-tert-Butoxycarbonylamino-3-(4-ethoxy-phenyl)-propionic acid methyl ester 
• 70642-86-3 N-(tert-butoxycarbonyl)-D-tyrosine 

Downstream Products

• 88718-86-9 Boc-Tyr(Et)-Har-OMe 
• 127106-75-6 [(S)-3-Diazo-1-(4-ethoxy-benzyl)-2-oxo-propyl]-carbamic acid tert-butyl ester 
• 2448-45-5 Cbz-D-Phe 
• 1443470-43-6 C₃₅H₄₁N₅O₁₀S 
• 1427310-90-4 C₂₃H₂₈BrN₃O₅ 
• 1427311-00-9 C₂₆H₂₉N₅O₄ 
• 1427310-75-5 C₂₁H₂₁N₅O₂ 
• 77452-98-3 Boc-Tyr(Et)-Phe-Val-Asn-Cys(Bzl)-Pro-D-Arg(Tos)-Gly-NH₂ 

Relevant articles and documents

NOVEL PROCESS FOR THE PREPARATION OF GADOLINIUM COMPLEX OF (4S)-4-(4-ETHOXYBENZYL)-3,6,9-TRIS(CARBOXYLATOMETHYL)-3,6,9- TRIAZAUNDECANEDIOIC ACID DISODIUM (GADOXETATE DISODIUM)

The present invention discloses a novel process for the preparation of gadolinium complex of (4S)-4-(4-Ethoxybenzyl)-3,6,9-tris(carboxylatomethyl)-3,6,9- triazaundecanedioic acid disodium of formula 1 and novel intermediates thereof.

Simplified Method for O-Alkylation of N-Protected Tyrosines

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Design of more potent antagonists of the antidiuretic responses to arginine-vasopressin

As part of a program aimed at designing more potent and selective antagonists of the antidiuretic responses to arginine-vasopressin (AVP), the authors substituted O-alkyl-D-tyrosine (where alkyl=methyl, ethyl, isopropyl, or n-propyl) at position 2 in our