24736-82-1Relevant articles and documents
Base promoted regioselective aromatization for the preparation of substituted 3-hydroxybenzene dicarboxylate
Guo, Weihang,Wang, Xianheng,Zhao, Changkuo,Wang, Yuhe
, p. 3167 - 3172 (2020)
A new convenient base promoted aromatization process has been developed to prepare substituted 3-hydroxybenzene dicarboxylate using commercially available materials. In particular, regioselectivity will occur for substrates with mono-substitution at 5- or
Metallo-β-lactamase inhibitory activity of 3-alkyloxy and 3-amino phthalic acid derivatives and their combination effect with carbapenem
Hiraiwa, Yukiko,Morinaka, Akihiro,Fukushima, Takayoshi,Kudo, Toshiaki
, p. 5841 - 5850 (2013/09/12)
3-Alkyloxy and 3-amino phthalic acid derivatives were found to have metallo-β-lactamase inhibitory activity. Among them, 3-amino phthalic acid derivatives showed both potent activity against metallo-β-lactamase, IMP-1 inhibitory activity and a strong combination effect with biapenem (BIPM), carbapenem antibiotic. In particular, the 4′-hydroxy-piperidine derivative showed strong IMP-1 inhibitory activity and a combination effect with various antibiotics.