247580-99-0

Basic information

• Product Name: 3-Ethyl-5-[2-(2-methoxyethoxy)-5-[4-(prop-1-yl)piperazin-1-ylsulphonyl]pyridin-3-yl]-2-(pyridin-2-yl)methyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
• Synonyms: 3-Ethyl-5-[2-(2-methoxyethoxy)-5-[4-(prop-1-yl)piperazin-1-ylsulphonyl]pyridin-3-yl]-2-(pyridin-2-yl)methyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
• CAS NO: 247580-99-0
• Molecular Weight: 596.71
• Mol File: 247580-99-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Ethyl-5-[2-(2-methoxyethoxy)-5-[4-(prop-1-yl)piperazin-1-ylsulphonyl]pyridin-3-yl]-2-(pyridin-2-yl)methyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Ethyl-5-[2-(2-methoxyethoxy)-5-[4-(prop-1-yl)piperazin-1-ylsulphonyl]pyridin-3-yl]-2-(pyridin-2-yl)methyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one(247580-99-0)
• EPA Substance Registry System: 3-Ethyl-5-[2-(2-methoxyethoxy)-5-[4-(prop-1-yl)piperazin-1-ylsulphonyl]pyridin-3-yl]-2-(pyridin-2-yl)methyl-2,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one(247580-99-0)

Safety Data

• Hazardous Substances Data: 247580-99-0(Hazardous Substances Data)

Relevant articles and documents

Pyrazolopyrimidinone cGMP PDE5 inhibitors for the treatment of sexual dysfunction

Compounds of the formulae (IA) and (IB): wherein R1is C1to C3alkyl optionally substituted with phenyl, Het or a N-linked heterocyclic group selected from piperidinyl and morpholinyl; wherein said phenyl group is optionally substituted by one or more substitutents selected from C1to C4alkoxy; halo; CN; CF3; OCF3or C1to C4alkyl wherein said C1to C4alkyl group is optionally substituted by C1to C4haloalkyl or haloalkoxy either of which is substituted by one or more halo atoms; R2is C1to C6alkyl and R13is OR3or NR5R6, or pharmaceutically or veterinarily acceptable salts thereof, or pharmaceutically or veterinarily acceptable solvates of either entity are potent and selective inhibitors of type 5 cyclic guanosine 3′,5′-monophosphate phosphodiesterase (cGMP PDE5) and have utility in the treatment of, inter alia, male erectile dysfunction (MED) and female sexual dysfunction (FSD).