247594-36-1Relevant articles and documents
Site-specific RNA cleavage using terpyridine · Cu(II)-linked 2'-O- methyloligonucleotides
Inoue, Hideo,Shimizu, Masaki,Furukawa, Takako,Tamura, Takashi,Matsui, Miwa,Ohtsuka, Eiko
, p. 1503 - 1505 (1999)
2'-Deoxy- and 2'-O-methyl-5'-O-terpyridyl derivatives of adenosine and cytidine were synthesized and used to construct 5'-end-modified oligonucleotides. These antisense agents complexed with Cu(II) exclusively cleaved a complementary RNA oligomer at the s