24781-10-0

Basic information

• Product Name: 1-benzyl-2,6-dimethyl-1H-benzo[d]imidazole
• Synonyms: 1-benzyl-2,6-dimethyl-1H-benzo[d]imidazole
• CAS NO: 24781-10-0
• Molecular Weight: 236.316
• Mol File: 24781-10-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-benzyl-2,6-dimethyl-1H-benzo[d]imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-2,6-dimethyl-1H-benzo[d]imidazole(24781-10-0)
• EPA Substance Registry System: 1-benzyl-2,6-dimethyl-1H-benzo[d]imidazole(24781-10-0)

Safety Data

• Hazardous Substances Data: 24781-10-0(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 1792-41-2 2,6-dimethyl-1H-benzo[d]imidazole 
• 1195791-02-6 C₁₆H₁₇BrN₂ 

Relevant articles and documents

An efficient strategy for N-alkylation of benzimidazoles/imidazoles in SDS-aqueous basic medium and N-alkylation induced ring opening of benzimidazoles

A sustainable route for the N-1 alkylation of imidazole and benzimidazole derivatives has been developed under volatile organic solvent free condition in alkaline water-SDS system. Incorporation of SDS in the reaction medium enhances the reaction rate by suppressing the solubility issue that arises for different substrates. This method provides high yield of the alkylated product in a shorter reaction time. For reactive alkyl halides reaction proceeds at ambient temperature whereas in the cases of less reactive alkyl halides require 55–60 °C to complete alkylation process. N-alkylation induced ring opening of the heterocyclic ring in benzimidazole derivatives to multifunctional aromatic compounds were noticed at 60 °C when more than two equivalents of alkyl halide was used.