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247923-41-7

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247923-41-7 Usage

General Description

N-[(1S,2S)-2-amino-1,2-diphenylethyl]-2,4,6-tris(1-methylethyl)-benzenesulfonamide is a chemical compound with a complex structure. It contains a sulfonamide functional group attached to a tris(1-methylethyl)benzene ring, and an amino-diphenylethyl group. N-[(1S,2S)-2-aMino-1,2-diphenylethyl]-2,4,6-tris(1-Methylethyl)-BenzenesulfonaMide is used in the pharmaceutical industry for the synthesis of potential drug candidates. It may have applications as an organic building block for the development of new therapeutic agents or as a research tool in medicinal chemistry. Its properties and potential uses make it an interesting target for further study in drug development and chemical synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 247923-41-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,7,9,2 and 3 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 247923-41:
(8*2)+(7*4)+(6*7)+(5*9)+(4*2)+(3*3)+(2*4)+(1*1)=157
157 % 10 = 7
So 247923-41-7 is a valid CAS Registry Number.

247923-41-7Downstream Products

247923-41-7Relevant articles and documents

Reaction development and mechanistic study of a ruthenium catalyzed intramolecular asymmetric reductive amination en route to the dual orexin inhibitor suvorexant (MK-4305)

Strotman, Neil A.,Baxter, Carl A.,Brands, Karel M. J.,Cleator, Ed,Krska, Shane W.,Reamer, Robert A.,Wallace, Debra J.,Wright, Timothy J.

, p. 8362 - 8371 (2011)

The first example of an intramolecular asymmetric reductive amination of a dialkyl ketone with an aliphatic amine has been developed for the synthesis of Suvorexant (MK-4305), a potent dual Orexin antagonist under development for the treatment of sleep di

Catalytic asymmetric Michael addition with curcumin derivative

Li, Wenjun,Wu, Wenbin,Yu, Feng,Huang, Huicai,Liang, Xinmiao,Ye, Jinxing

supporting information; experimental part, p. 2505 - 2511 (2011/05/06)

Catalytic asymmetric Michael additions with curcumin derivatives were achieved by a new series of tertiary amine-thiourea organocatalysts to afford the Michael adducts in high yields and excellent enantioselectivities.

Chemistry of opium alkaloids, 45. Improvements in the total synthesis of morphine

Meuzelaar, Gerrit J.,Van Vliet, Michiel C. A.,Maat, Leendert,Sheldon, Roger A.

, p. 2315 - 2321 (2007/10/03)

The chiral 1,2,3,4-tetrahydroisoquinoline intermediates in the Price and Beyerman routes to morphine, (+)-(R)-1-(3-hydroxy-4-methoxybenzyl)-6-methoxy- 1,2,3,4-tetrahydroisoquinoline (6) and (+)-(R)-1-(3,5-dibenzyloxy-4- methoxybenzyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline (5), were prepared in high ee by ruthenium-catalyzed asymmetric transfer hydrogenation of the corresponding imine precursors (Noyori method). The yield of the key raw material in the Beyerman route, 3,5-dibenzyloxy-4-methoxyphenylacetric acid (1), starting from gallic acid methyl ester (7) was improved by a factor of 5 over previously described syntheses. Key steps in the new procedure are the selective formation of methyl 3,5-dihydroxy-4-methoxybenzoate (9) via the 3,5-diacetate and an improved benzylation of the hydroxyl groups in 9.

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