24807-55-4 Usage
Description
3-Nitro-1,2,4-triazole is an organic compound characterized by its light yellow solid appearance. It is a heterocyclic compound with a triazole ring structure, featuring a nitro group at the 3rd position. 3-Nitro-1,2,4-triazole is known for its unique chemical properties and potential applications in various fields.
Uses
Used in Oligonucleotide Synthesis:
3-Nitro-1,2,4-triazole is utilized as a synthetic building block in the creation of oligonucleotides, which are short sequences of nucleic acids. These oligonucleotides have significant applications in molecular biology, genetic research, and the development of new therapeutic strategies.
Used in Radiosensitization:
In the field of radiotherapy, 3-Nitro-1,2,4-triazole serves as a radiosensitizer, specifically for hypoxic cells in vitro. Radiosensitizers are compounds that enhance the sensitivity of cells to the effects of ionizing radiation, thereby improving the effectiveness of radiation treatments for cancer. By increasing the radiosensitivity of hypoxic cells, 3-Nitro-1,2,4-triazole contributes to the overall success of radiation therapy in targeting cancerous cells.
Check Digit Verification of cas no
The CAS Registry Mumber 24807-55-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,8,0 and 7 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 24807-55:
(7*2)+(6*4)+(5*8)+(4*0)+(3*7)+(2*5)+(1*5)=114
114 % 10 = 4
So 24807-55-4 is a valid CAS Registry Number.
InChI:InChI=1/C2H2N4O2/c7-6(8)2-3-1-4-5-2/h1H,(H,3,4,5)
24807-55-4Relevant articles and documents
Synthesis and structure of new ditopic ligands containing tetrazole and 3-nitro-1,2,4-triazole fragments
Grigor'Ev, Yu. V.,Voitekhovich,Lyakhov,Ivashkevich,Buglak,Ivashkevich
, p. 742 - 746 (2014)
Alkylation of 3-nitro-1,2,4-triazole with haloalkyltetrazoles has afforded in high yields previously unknown 1-[2-(3-nitro-1H-1,2,4-triazol-1-yl)ethyl]-1H- tetrazole and 2-tert-butyl-5-(3-nitro-1H-1,2,4-triazol-1-ylmethyl)-2H-tetrazole. The molecular and crystal structure of these compounds has been established by X-ray diffraction analysis (XRD).
A green and facile approach for synthesis of nitro heteroaromatics in water
Zhao, Xiu X.,Zhang, Ji C.,Li, Sheng H.,Yang, Qing P.,Li, Yu C.,Pang, Si P.
, p. 886 - 890 (2014/08/05)
A convenient and green method for the oxidation of nitrogen-rich heterocyclic amines to nitro-substituted heteroaromatics using potassium peroxymonosulfate (2KHSO5·KHSO4·K 2SO4, Oxone) in water was developed. This method has several advantages over previous methods: operational simplicity, safety, inexpensive reagents, the use of H2O as the sole solvent, and mild conditions. The utility of the present oxidative system was demonstrated by the synthesis of the important energetic compounds 3,4,5-trinitro-1H-pyrazole (TNP) and 5-amino-3-nitro-1H-1,2,4-triazole (ANTA).
Oxidation of 3-Amino-1,2,4-triazoles to 3-Nitro-1,2,4-triazoles with Sodium Perborate
Tolstyakov,Pevzner
, p. 1803 - 1804 (2007/10/03)
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