24835-08-3 Usage
Description
2-Nitrobenzylamine hydrochloride is an organic compound with the chemical formula C7H7N2O2·HCl. It is a derivative of benzylamine, featuring a nitro group (-NO2) at the 2nd position of the benzene ring and a hydrochloride (HCl) group attached to the amine functionality. 2-NITROBENZYLAMINE HYDROCHLORIDE is known for its reactivity and is commonly utilized in various chemical synthesis processes.
Uses
Used in Chemical Synthesis Studies:
2-Nitrobenzylamine hydrochloride is used as a reactant in chemical synthesis studies, particularly for the preparation of various organic compounds with potential applications in pharmaceuticals, materials science, and other fields.
Used in Pharmaceutical Industry:
2-Nitrobenzylamine hydrochloride is used as a key intermediate in the synthesis of tetrahydroisoquinolines via Heck-aza-Michael reactions. These tetrahydroisoquinolines are important scaffolds in the development of novel pharmaceuticals targeting various biological pathways.
Used in Factor Xa Inhibition:
In the pharmaceutical industry, 2-Nitrobenzylamine hydrochloride is also used as a building block for the synthesis of aminomethylphenylamine scaffolds. These scaffolds are crucial in the development of factor Xa inhibitors, which are potential anticoagulant drugs for the treatment of thrombotic disorders.
Used in Mannosyltransferase Inhibition:
2-Nitrobenzylamine hydrochloride is employed as a reactant in the synthesis of squaryliamides, which are known inhibitors of mannosyltransferase enzymes. These enzymes play a significant role in the biosynthesis of glycoconjugates, and their inhibition can have therapeutic implications in cancer and other diseases.
Used in Fluorescent Two-Photon Absorption Dyes:
In the field of materials science, 2-Nitrobenzylamine hydrochloride is used as a precursor for the development of fluorescent two-photon absorption benzothiadiazole dyes. These dyes have potential applications in bioimaging, sensing, and optoelectronic devices due to their unique optical properties.
Check Digit Verification of cas no
The CAS Registry Mumber 24835-08-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,8,3 and 5 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 24835-08:
(7*2)+(6*4)+(5*8)+(4*3)+(3*5)+(2*0)+(1*8)=113
113 % 10 = 3
So 24835-08-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H8N2O2.ClH/c8-5-6-3-1-2-4-7(6)9(10)11;/h1-4H,5,8H2;1H
24835-08-3Relevant articles and documents
Bambusurils Bearing Nitro Groups and Their Further Modifications
Yawer, Mirza Arfan,Sleziakova, Kristina,Pavlovec, Lukas,Sindelar, Vladimir
, p. 41 - 47 (2018/01/17)
Bambusurils are recently developed neutral anion receptors that show a high affinity towards many inorganic anions, not only in organic solvents but also in water. However, the number of water-soluble bambusurils and also those bearing functional groups is very limited. In this paper we report the synthesis of four- and six-membered bambusurils containing eight and twelve nitro groups. All the nitro groups on the bambusuril portals could be transformed into amino functions, which provided the macrocycles with water solubility and allowed their further modification. For example, we have demonstrated the conversion of amino groups on the bambusurils into the corresponding urea-functionalized bambusuril derivatives. We also report the first example of a bambusuril bearing only two functional groups, which was prepared by the condensation of two different glycolurils.
