24860-78-4 Usage
Chemical Class
Piperidines
Physical State
White to off-white solid
Solubility
Soluble in organic solvents
Melting Point
Around 150-155°C
Use
Pharmaceutical intermediate
Potential Applications
Building block for the synthesis of various pharmaceutical drugs
Pharmacological Properties
Potential central nervous system stimulant
Check Digit Verification of cas no
The CAS Registry Mumber 24860-78-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,8,6 and 0 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 24860-78:
(7*2)+(6*4)+(5*8)+(4*6)+(3*0)+(2*7)+(1*8)=124
124 % 10 = 4
So 24860-78-4 is a valid CAS Registry Number.
InChI:InChI=1/C22H27NO2/c24-21(15-10-18-23-16-8-3-9-17-23)22(25,19-11-4-1-5-12-19)20-13-6-2-7-14-20/h1-2,4-7,11-14,25H,3,8-10,15-18H2
24860-78-4Relevant articles and documents
Synthesis and antagonistic activity at muscarinic receptor subtypes of some derivatives of diphenidol
Varoli, Lucilla,Angeli, Piero,Buccioni, Michela,Burnelli, Silvia,Cavalli, Andrea,Marucci, Gabriella,Recanatini, Maurizio
, p. 651 - 657 (2007/10/03)
A series of new derivatives, related to diphenidol and to its 2-carbonyl analogue, were designed as antimuscarinic agents. The synthesized compounds were evaluated both as hydrochlorides and as methiodides by functional tests at guinea-pig heart (M2), guinea-pig ileum (M3) and rabbit vas deferens (putative M4). Two derivatives (3a and 5a) showed an M3-selective profile similar to that of the reference compounds, though they resulted less potent.
