24880-45-3 Usage
Description
CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID, also known as all-cis-7,10,13,16,19-Docosapentaenoic Acid or DPA, is an omega-3 fatty acid found in fish oils. It is a minor constituent of the total serum unsaturated fatty acids in humans, ranging from 0.1 to 1%, and its levels can increase with dietary supplementation. DPA is a C22 polyunsaturated fatty acid with five double bonds in the 7-, 10-, 13-, 16-, and 19-positions. It is associated with neurological and ocular health benefits and has been studied for its potential as a biomarker for cardiovascular disease, nutritional, and metabolic disorders.
Uses
Used in Pharmaceutical Applications:
CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID is used as an inhibitor of platelet aggregation for preventing blood clot formation. It blocks the cyclooxygenase pathway and stimulates the lipoxygenase pathway, effectively inhibiting platelet aggregation and reducing the risk of cardiovascular events.
Used in Nutritional Supplements:
CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID is used as a nutraceutical ingredient for promoting neurological and ocular health. Its supplementation can help increase the levels of DPA in the human body, which is associated with various health benefits.
Used in Research and Diagnostics:
CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID is used as a Certified Spiking Solution in mass spectrometry-based fatty acid testing applications. It is essential for the assessment of cardiovascular disease risk, fatty acid deficiency, and the detection and quantification of docosapentaenoic acid in nutraceuticals and dietary supplements.
Used in the Food Industry:
CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID is used as an additive in the food industry to enhance the health benefits of products, particularly those rich in omega-3 fatty acids. It can be incorporated into supplements, fortified foods, and other products to improve their nutritional profile and support cardiovascular health.
Used in the Cosmetics Industry:
CIS-7,10,13,16,19-DOCOSA-PENTAENOIC ACID can be used in the cosmetics industry for its potential benefits to skin health, including anti-inflammatory and antioxidant properties. It may be incorporated into skincare products to promote healthy skin and reduce the signs of aging.
Check Digit Verification of cas no
The CAS Registry Mumber 24880-45-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,4,8,8 and 0 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 24880-45:
(7*2)+(6*4)+(5*8)+(4*8)+(3*0)+(2*4)+(1*5)=123
123 % 10 = 3
So 24880-45-3 is a valid CAS Registry Number.
InChI:InChI=1/C22H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22(23)24/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-21H2,1H3,(H,23,24)/b4-3-,7-6-,10-9-,13-12-,16-15-
24880-45-3Relevant articles and documents
A Convenient Protocol for the Synthesis of Fatty Acid Amides
Johansson, Silje J. R.,Johannessen, Tonje,Ellefsen, Christiane F.,Ristun, Mali S.,Antonsen, Simen,Hansen, Trond V.,Stenstrom, Yngve,Nolsoe, Jens M. J.
, p. 213 - 217 (2019/01/14)
Several classes of biologically occurring fatty acid amides have been reported from mammalian and plant sources. Many amides conjugated with fatty acids of mammalian origin exhibit specific activation of individual receptors. Their potential as pharmacological tools or as lead compounds towards the development of novel therapeutics is of great interest. Hence, access to such amides by a practical, high-yielding and scalable protocol without affecting the geometry or position of sensitive functionalities is needed. A protocol that meets all these requirements involves activation of the corresponding acid with carbonyl diimidazole (CDI) followed by reaction with the desired amine or its hydrochloride. More than fifty compounds have been prepared in generally high yields.
One-pot synthesis of polyunsaturated fatty acid amides with anti-proliferative properties
Tremblay, Hugo,St-Georges, Catherine,Legault, Marc-Andr,Morin, Caroline,Fortin, Samuel,Marsault, Eric
, p. 5635 - 5638 (2015/01/09)
A one-pot environmentally friendly transamidation of ω-3 fatty acid ethyl esters to amides and mono- or diacylglycerols was investigated via the use of a polymer-supported lipase. The method was used to synthesize a library of fatty acid monoglyceryl esters and amides. These new derivatives were found to have potent growth inhibition effects against A549 lung cancer cells.
PROCESS FOR PREPARING AND PURIFYING FATTY ACIDS
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Page/Page column 19, (2011/08/21)
There is provided a process for purifying a fatty acid, which process comprises reacting a fatty acid with a lithium salt in a first solution and under conditions to allow formation of a precipitate of a lithium salt of the fatty acid; isolating the precipitate; dissolving the precipitate in a second solution followed by separation of the organic and aqueous layers so formed; and evaporating the organic layer to isolate the purified fatty acid. There is also provided a process for increasing the length of a fatty acid, and the use of a lithium salt to purify a fatty acid.
