24885-48-1

Basic information

• Product Name: 2-bromo-6-ethylphenol
• CAS NO: 24885-48-1
• Molecular Formula: C₈H₉BrO
• Molecular Weight: 201.0605
• Mol File: 24885-48-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 227.2°C at 760 mmHg
• Flash Point: 91.2°C
• Density: 1.469g/cm³
• Vapor Pressure: 0.0523mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: 2-bromo-6-ethylphenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-6-ethylphenol(24885-48-1)
• EPA Substance Registry System: 2-bromo-6-ethylphenol(24885-48-1)

Safety Data

• Hazardous Substances Data: 24885-48-1(Hazardous Substances Data)

Upstream product

• 90-00-6 o-Hydroxyethylbenzene 

Downstream Products

• 1395499-08-7 2-ethyl-4-(2,2,2-trifluoro-1-hydroxy-ethyl)-phenol 
• 1395499-03-2 C₁₀H₁₀BrF₃O₂ 
• 1429416-11-4 C₂₀H₂₁BBrOP 
• 1643966-25-9 bis[2-(diphenylphosphanyl)-6-ethylphenyl] (4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-dicarboxylate 
• 1429416-15-8 2-boranatodiphenylphosphanyl-6-ethylphenol 
• 1643966-16-8 (4S,5S)-4,5-bis{[2-(diphenylphosphanyl)-6-ethylphenoxy]methyl}-2,2-dimethyl-1,3-dioxolane 
• 797784-43-1 3-bromo-5-ethyl-4-hydroxybenzaldehyde 

Relevant articles and documents

Chiral Phosphine–Phosphite Ligands in Asymmetric Gold Catalysis: Highly Enantioselective Synthesis of Furo[3,4-d]-Tetrahydropyridazine Derivatives through [3+3]-Cycloaddition

The AuI-catalyzed reaction of 2-(1-alkynyl)-2-alken-1-ones with azomethine imines regio- and diastereoselectively affords furo[3,4-d]tetrahydropyridazines in a tandem cyclization/intermolecular [3+3]-cycloaddition process under mild conditions.

Synthesis of C2-symmetric bisphosphine ligands from tartaric acid, and their performance in the Pd-Catalyzed asymmetric o-allylation of a phenol

Starting from tartaric acid derived chiral diols or dicarboxylic acid dichlorides with either a 2,2-dimethyl-1,3-dioxolane (Taddol) or a 2,3-dimethoxy-2,3-dimethyl-1,4-dioxane (Tatrol) core structure, and BH 3-protected ortho-phosphanyl phenols, a set of fourteen new C 2-symmetric diphosphine ligands was synthesized. In addition, three related ligands were obtained from ortho-diphenylphosphino-anilines. The fully characterized ligands were then tested in the Pd-catalyzed enantioselective O-allylation of 4-methoxyphenol using crotyl methyl carbonate as a reagent. In addition, a pseudo-intramolecular variant of the reaction, using crotyl 4-methoxyphenyl carbonate as a substrate, was studied. The so-called Trost ligand was used as a reference. Although the Trost ligand (3 mol-%) gave up to 84% ee, one of the new ligands showed higher activity (50% ee with 0.075 mol-%). Copyright

Substrate-Based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase

High levels of striatal-enriched protein tyrosine phosphatase (STEP) activity are observed in a number of neuropsychiatric disorders such as Alzheimer's disease. Overexpression of STEP results in the dephosphorylation and inactivation of many key neuronal