2494-12-4

Basic information

• Product Name: N-acetyldopamine
• Synonyms: N-acetyldopamine
• CAS NO: 2494-12-4
• Molecular Formula: C₁₀H₁₃NO₃
• Molecular Weight: 195.22
• Mol File: 2494-12-4.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 486.7°Cat760mmHg
• Flash Point: 248.1°C
• Appearance: /
• Density: 1.235g/cm³
• Vapor Pressure: 4.27E-10mmHg at 25°C
• Refractive Index: 1.578
• Storage Temp.: −20°C
• PKA: 9.80±0.10(Predicted)
• CAS DataBase Reference: N-acetyldopamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-acetyldopamine(2494-12-4)
• EPA Substance Registry System: N-acetyldopamine(2494-12-4)

Safety Data

• RTECS: AB7651000
• Hazardous Substances Data: 2494-12-4(Hazardous Substances Data)

Usage

General Description

N-acetyldopamine is a naturally occurring chemical compound that is derived from dopamine, a neurotransmitter in the brain. It has attracted attention as a potential ingredient in cosmetic and pharmaceutical products due to its antioxidant and UV-absorbing properties. N-acetyldopamine has been shown to have protective effects on skin cells against oxidative stress and UV radiation, which makes it a promising candidate for use in anti-aging and sun protection products. Additionally, it has been investigated for its potential role in treating neurodegenerative diseases, as it may have neuroprotective effects in the brain. Overall, N-acetyldopamine shows promise as a multifunctional compound with various potential applications in the fields of cosmetics and medicine.

InChI:InChI=1/C10H13NO3/c1-7(12)11-5-4-8-2-3-9(13)10(14)6-8/h2-3,6,13-14H,4-5H2,1H3,(H,11,12)

Upstream product

• 55174-61-3 2-(3,4-dimethoxyphenyl)propan-1-amine 
• 6275-29-2 N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide 
• 62-31-7 dopamine hydrochloride 
• 108-24-7 acetic anhydride 
• 76734-99-1 2-(3',4'-dihydroxyphenyl)-3-acetylamino-6-(N-acetyl-2''-aminoethyl)-2,3-dihydro-1,4-benzodioxin 
• 51-61-6 dopamine 
• 128459-09-6 N-acetyl-N-methoxyacetamide 
• 645-31-8 3-hydroxytyramine hydrobromide 
• 120-20-7 2-(3,4-dimethoxyphenyl)-ethylamine 
• 75-36-5 acetyl chloride 

Downstream Products

• 76734-99-1 2-(3',4'-dihydroxyphenyl)-3-acetylamino-6-(N-acetyl-2''-aminoethyl)-2,3-dihydro-1,4-benzodioxin 
• 6275-29-2 N-[2-(3,4-dimethoxyphenyl)ethyl]acetamide 
• 188987-95-3 C₁₄H₁₈N₄O₄ 
• 176226-41-8 C₁₈H₂₂N₄O₆ 
• 145873-65-0 C₁₈H₂₂N₄O₆ 
• 452094-39-2 C₁₅H₁₆N₆O₄ 
• 1220911-01-2 C₁₆H₁₆BNO₃ 
• 14522-07-7 2-oxo-N-acetyldopamine 
• 499-61-6 arterenone 
• 51-61-6 dopamine 
• 161236-57-3 5-(2-acetamidoethyl)-2-hydroxy-1,4-benzoquinone 
• 146004-49-1 4a,8-bis-(2-acetamidoethyl)-4-<2-(2-acetamidoethyl)-4,5-dihydroxyphenyl>-10-(2-carboethyl)-3-hydroxy-2,4a-dihydro-10H-phenoxazin-2-one 
• 146004-48-0 4a,7-bis-(2-acetamidoethyl)-4-<2-(2-acetamidoethyl)-4,5-dihydroxyphenyl>-10-(2-carboethyl)-3-hydroxy-2,4a-dihydro-10H-phenoxazin-2-one 
• 137197-04-7 N^α-Acetyl-N^τ-<1-(3,4-dihydroxyphenyl)-2-N-acetylamino-ethyl>-histidine 

Relevant articles and documents

Acylated serine derivatives: A unique class of arthropod pheromones of the Australian redback spider, Latrodectus hasselti

(Figure Presented) Irresistible: Amino acid derivatives are very rarely used as pheromones by arthropods. The widow spider Latrodectus hasselti (see picture) uses a unique compound (see formula) to lure its males. The molecular configuration plays an impo

The chemical reactivities of DOPA and dopamine derivatives and their regioselectivities upon oxidative nucleophilic trapping

The chemical reactivities of four catecholamines, N-acetyl dopamine (NADA) and its dehydro derivative (NAΔDA), N-acetyl 3,4-dihydroxy-phenylalanine methyl ester (NADOPAME) and its dehydro derivative (NAΔDOPAME), under oxidative nucleophilic trapping and p

Asymmetric Transfer Hydrogenation of Unhindered and Non-Electron-Rich 1-Aryl Dihydroisoquinolines with High Enantioselectivity

The use of arene/Ru/TsDPEN catalysts bearing a heterocyclic group on the TsDPEN in the asymmetric transfer hydrogenation (ATH) of dihydroisoquinolines (DHIQs) containing meta- or para-substituted aromatic groups at the 1-position results in the formation of products of high enantiomeric excess. Previously, only 1-(ortho-substituted)aryl DHIQs, or with an electron-rich fused ring gave products with high enantioselectivity; therefore, this approach solves a long-standing challenge for imine ATH.

Synthesis of catecholamine conjugates with nitrogen-centered bionucleophiles

The enzymatic (tyrosinase) and chemical (NaIO4, Ag2O or Fremys's salt) oxidation of biologically relevant catecholamines, such as dopamine (DA), N-acetyldopamine (NADA) and the Ecstasy metabolites (α-MeDA and N-Me-α-MeDA) generates t