2496-90-4

Basic information

• Product Name: 4-HYDROXYBENZOIC ACID 2-HYDROXYETHYL ESTER
• Synonyms: 4-HYDROXYBENZOIC ACID 2-HYDROXYETHYL ESTER;2-HYDROXYETHYL 4-HYDROXYBENZOATE;2-HYDROXYETHYL P-HYDROXYBENZOATE;2-HYDROXYETHYLPARABEN;4-HYDROXYBENZOIC ACID 2-HYDROXYETHYL ESTER 98+%;4-Hydroxybenzoic acid 2-hydroxyethul ester;4-Hydroxybenzoic Acid 2-Hydroxyethyl Ester 2-Hydroxyethylparaben
• CAS NO: 2496-90-4
• Molecular Formula: C₉H₁₀O₄
• Molecular Weight: 182.17
• Mol File: 2496-90-4.mol
• Article Data: 1

Chemical Properties

• Melting Point: 141 °C
• Boiling Point: 202 °C / 2.4mmHg
• Flash Point: 152.7 °C
• Appearance: /
• Density: 1.303 g/cm³
• Vapor Pressure: 3.85E-06mmHg at 25°C
• Refractive Index: 1.573
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 8.07±0.15(Predicted)
• CAS DataBase Reference: 4-HYDROXYBENZOIC ACID 2-HYDROXYETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-HYDROXYBENZOIC ACID 2-HYDROXYETHYL ESTER(2496-90-4)
• EPA Substance Registry System: 4-HYDROXYBENZOIC ACID 2-HYDROXYETHYL ESTER(2496-90-4)

Safety Data

• Statements: 36
• Safety Statements: 26
• Hazardous Substances Data: 2496-90-4(Hazardous Substances Data)

Usage

General Description

4-Hydroxybenzoic acid 2-hydroxyethyl ester is a chemical compound that is a derivative of 4-hydroxybenzoic acid, commonly known as paraben. It is commonly used in cosmetics and personal care products as a preservative due to its antimicrobial properties. 4-HYDROXYBENZOIC ACID 2-HYDROXYETHYL ESTER is also used in pharmaceuticals as an excipient or an inactive ingredient that helps deliver the active ingredients of a medication. It is a clear, colorless liquid with a slightly sweet odor and is considered to be safe for use in low concentrations, although there is ongoing research into its potential effects on human health.

InChI:InChI=1/C9H10O4/c10-5-6-13-9(12)7-1-3-8(11)4-2-7/h1-4,10-11H,5-6H2

Upstream product

• 120-47-8 Ethyl 4-hydroxybenzoate 
• 57045-26-8 4-Ethoxycarbonyloxybenzoyl chloride 
• 15552-32-6 4-Ethoxycarbonyloxybenzoic acid 
• 107-07-3 2-chloro-ethanol 

Downstream Products

• 1609114-83-1 2-hydroxyethyl 4-(1,1,2-trifluoro-2-(1,1,2,3,3,3-hexafluoro-2-(perfluoropropoxy)propoxy)ethoxy)benzoate 

Relevant articles and documents

Solar photocatalytic decomposition of ethyl paraben in zinc oxide suspensions

The photocatalytic degradation of ethyl paraben (EP) in zinc oxide (ZnO) suspensions under simulated solar radiation was investigated. The effect of EP concentration (500–1500 μg/L), ZnO concentration (100–500 mg/L), reaction time (3–9 min), initial pH (3–9), light intensity (7.3 10?7–1.1 10?6 einstein/(L.s)) and the water matrix (0–10 mg/L of humic acid) on degradation was evaluated implementing a factorial design methodology. Of the six variables tested, EP concentration, ZnO concentration, reaction time and the water matrix were found to be statistically significant variables, and also important was the second order interaction of EP concentration with reaction time. With the exception of the water matrix, all other effects were positive with respect to the concentration of EP removed. Experiments at increased EP concentration (20 mg/L) were performed to identify transformation products (TPs) and assess the extent of mineralization. LC-TOF-MS analysis revealed the formation of seven early-stage TPs through hydroxylation and dealkylation reactions and a plausible reaction pathway was proposed. Besides the identified TPs, other unidentified TPs were also formed as has been verified measuring the extent of mineralization and performing a carbon balance in the liquid phase. EP at 20 mg/L exhibited mild estrogenic activity, which was partially removed upon oxidation. The stability of ZnO was evaluated measuring the extent of zinc leaching, which was just 1.5%; moreover, ZnO was found to be more active than reference P25 TiO2 for EP degradation and mineralization.