24973-50-0

Basic information

• Product Name: 3-CYANOBIPHENYL
• Synonyms: 3-CYANOBIPHENYL;3-CYANODIPHENYL;m-Phenyl Benzonitrile;3-Phenylbenzonitrile;[1,1'-biphenyl]-3-carbonitrile
• CAS NO: 24973-50-0
• Molecular Formula: C₁₃H₉N
• Molecular Weight: 179.22
• Product Categories: Aromatic Nitriles
• Mol File: 24973-50-0.mol
• Article Data: 12

Chemical Properties

• Melting Point: 44-46°C
• Boiling Point: 140°C 1mm
• Flash Point: 151.8 °C
• Appearance: /
• Density: 1.11 g/cm³
• CAS DataBase Reference: 3-CYANOBIPHENYL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CYANOBIPHENYL(24973-50-0)
• EPA Substance Registry System: 3-CYANOBIPHENYL(24973-50-0)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22
• Safety Statements: 22-26-36/37/39
• RIDADR: 3439
• HazardClass: IRRITANT
• Hazardous Substances Data: 24973-50-0(Hazardous Substances Data)

Usage

General Description

3-Cyanobiphenyl is a chemical compound that belongs to the class of biphenyls, which are aromatic hydrocarbons composed of two benzene rings linked by a single bond. It is also known as 3-Phenylcyanobenzene and has the molecular formula C13H9N. 3-Cyanobiphenyl is a colorless to pale yellow liquid that is insoluble in water but soluble in organic solvents. It is commonly used as a precursor in the synthesis of liquid crystals and as a starting material for the production of pharmaceuticals and other organic compounds. This chemical is also known to have toxic properties and should be handled with caution.

Upstream product

• 623-26-7 terephthalonitrile 
• 67-56-1 methanol 
• 110-83-8 cyclohexene 
• 108-86-1 bromobenzene 
• 100-47-0 benzonitrile 
• 69113-59-3 3-iodobenzonitrile 
• 595-90-4 tetraphenyltin(IV) 
• 2974-92-7 3,4-dichlorobiphenyl 
• 42498-44-2 3-phenylbenzoyl chloride 
• 6952-59-6 3-cyanobromobenzene 
• 66152-74-7 3-<(trifluoromethanesulfonyl)oxy>benzonitrile 
• 603-33-8 triphenylbismuthane 
• 591-50-4 iodobenzene 
• 94-36-0 dibenzoyl peroxide 

Downstream Products

• 177976-49-7 3-phenylbenzylamine 
• 42498-35-1 N-(tert-butyl)-[1,1'-biphenyl]-3-carboxamide 
• 26130-63-2 [1,1‘-biphenyl]-3-carboximidamide 
• 1220526-67-9 2,4-di(3-biphenylyl)-6-[3,5-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,3,5-triazine 
• 1607454-69-2 6-([1,1'-biphenyl]-3-yl)-5-phenyl-3,4-dihydro-2H-pyran 
• 1314700-36-1 3-phenyl α,α-dimethylbenzylamine 
• 1397293-31-0 5-(3-(1-([1,1‘-biphenyl]-3-yl)cyclopropyl)ureido)-2-chlorobenzamide 
• 1397293-28-5 4-nitrophenyl (1-([1,1'-biphenyl]-3-yl)cyclopropyl)carbamate 
• 1268250-86-7 4,6-bis(biphenyl-3-yl)-2-[5-(9-phenathryl)-4'-(2-pyridyl)biphenyl-3-yl]-1,3,5-triazine 
• 1073062-76-6 2,4-bis({[1,1'-biphenyl]-3-yl})-6-(3,5-dibromophenyl)-1,3,5-triazine 

Relevant articles and documents

Ligand-Promoted Direct C-H Arylation of Simple Arenes: Evidence for a Cooperative Bimetallic Mechanism

A highly efficient catalyst for the direct C-H arylation of simple arenes was developed on the basis of a palladium-diimine complex. The developed catalyst exhibited the highest turnover number reported to date for the direct arylation of benzene due to increased stability provided by the diimine ligand. The reaction was also performed using only 2-3 equiv of simple arenes. Mechanistic studies in combination with kinetic measurements, isotope effect experiments, synthesis of possible intermediates, and stoichiometric reactions suggested that this reaction follows a cooperative bimetallic mechanism.

Palladium catalyzed cyanation of o-dichloroarenes with potassium hexacyanoferrate(ii)

Cyanation of o-dichloroarenes with potassium hexacyanoferrate(ii) catalyzed by Pd(OAc)2/PPh3 system gave the corresponding phthalodinitriles in moderate yields. The method of competitive reactions revealed that activation rate of chl

Pd(PPh3)4-PEG 400 catalyzed protocol for the atom-efficient stille cross-coupling reaction of organotin with aryl bromides

(Chemical Equation Presented) Aryl bromides (4 equiv) were coupled efficiently with organotin (1 equiv) in an atom-efficient way using the tetra(triphenylphosphine)palladium/polyethylene glycol 400 (Pd(PPh 3)4/PEG 400) catalytic syst