25062-90-2

Basic information

• Product Name: 1-Propanol, 3-(phenylsulfonyl)-
• Synonyms: 3-(phenylsulphonyl)propan-1-ol;3-benzenesulfonyl-propan-1-ol;3-phenylsulfonylpropanol;1-Propanol,3-(phenylsulfonyl);3-Benzolsulfonyl-propan-1-ol;1-phenylsulphonyl-3-hydroxypropane;3-(phenylsulfonyl)propan-1-ol;3-(phenylsulfonyl)-1-propanol
• CAS NO: 25062-90-2
• Molecular Formula: C9H12O3S
• Molecular Weight: 200.258
• Mol File: 25062-90-2.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: 1-Propanol, 3-(phenylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanol, 3-(phenylsulfonyl)-(25062-90-2)
• EPA Substance Registry System: 1-Propanol, 3-(phenylsulfonyl)-(25062-90-2)

Safety Data

• Hazardous Substances Data: 25062-90-2(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Solubility

Soluble in water

Uses

Reagent in organic synthesis, production of pharmaceuticals and agrochemicals, manufacturing of perfumes and flavorings, solvent in various chemical processes

Medical applications

Potential use as a prostaglandin inhibitor for the development of new therapeutic agents.

Upstream product

• 16212-05-8 (allylsulfonyl)benzene 
• 107-18-6 allyl alcohol 
• 80-17-1 benzenesufonyl hydrazide 
• 24536-40-1 3-phenylthiopropanol 
• 873-55-2 sodium benzenesulfonate 
• 627-18-9 1-bromo-3-propanol 
• 108-98-5 thiophenol 
• 930-69-8 sodium thiophenolate 
• 27098-65-3 3-phenylsulfanyl-propionaldehyde 
• 3112-85-4 methylphenylsulfonate 
• 75-07-0 acetaldehyde 
• 111086-99-8 2-(3-Phenylsulfanyl-propoxy)-tetrahydro-pyran 
• 67-56-1 methanol 
• 1121-30-8 1-hydroxy-2(1H)-pyridinethione 

Downstream Products

• 144343-20-4 3-Benzenesulfonyl-decan-1-ol 
• 121942-45-8 13-Benzenesulfonyl-15-(tert-butyl-dimethyl-silanyloxy)-pentadecanoic acid methyl ester 
• 65288-11-1 3-(phenylsulfonyl)propyl p-toluenesulfonate 
• 187161-39-3 1-(3-chloropropylsulfonyl)-3-nitrobenzene 
• 1421917-98-7 1-(3-fluoropropylsulfonyl)-3-nitrobenzene 
• 1421917-99-8 3-(3-chloropropylsulfonyl)aniline 
• 1421918-00-4 3-(3-fluoropropylsulfonyl)aniline 
• 1421918-01-5 C₂₀H₁₈ClFN₄O₄S 
• 1421918-02-6 N-4-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N-2-(3-(3-chloropropylsulfonyl)phenyl)pyrimidine-2,4-diamine 
• 1421918-03-7 N₄-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N₂-(3-(3-iodopropylsulfonyl)phenyl)pyrimidine-2,4-diamine 
• 1421918-04-8 3-(3-(4-(5-chlorobenzo-[d][1,3]dioxol-4-ylamino)pyrimidin-2-ylamino)phenylsulfonyl)propyl4-methylbenzenesulfonate 
• 1421917-97-6 C₂₀H₁₈Cl⁽¹⁸⁾FN₄O₄S 
• 19432-96-3 3-(phenylsulfonyl)propyl chloride 
• 495406-19-4 ((3-fluoropropyl)sulfonyl)benzene 

Relevant articles and documents

Sulfoxide and sulfone compounds, as well as selective synthesis method and application thereof

The invention discloses a method for selectively synthesizing a sulfoxide compound shown as a formula (II) and a sulfone compound shown as a formula (III). In a reaction solvent, thioether (I) is usedas a reaction raw material and oxygen as an oxidation reagent, under the catalytic action of visible light and a photosensitive reagent; under the assistance of an additive, when a large-polarity proton-containing additive such as an acid and an alcohol or a solvent or an additive with excellent electron donating ability is used, a sulfoxide compound (II) is selectively generated; and when a small-polarity aprotic additive or a solvent is used, a sulfone compound (III) is selectively generated. The synthesis method has the advantages of easily available and cheap raw materials, simple reaction operation, mild reaction conditions, high yield and excellent functional group tolerance. According to the invention, synthesis and modification of some medicines are realized, and an efficient method for selectively constructing sulfoxide and sulfone compounds is provided for medicinal chemistry research.

Synthesizing method of 3-sulfonyl alcohol compounds

The invention discloses a synthesizing method of 3-sulfonyl alcohol compound. The method includes: using substituted sulfohydrazide and propenol compounds as the raw materials to perform reaction in water so as to obtain the 3-sulfonyl alcohol compounds. The method has the advantages that the method uses the substituted sulfohydrazide and the propenol compounds as the raw materials to perform the heating reaction in an aqueous solution without catalysts to directly obtain the 3-sulfonyl alcohol compounds, and the 3-sulfonyl alcohol compounds with the purity being above 80% can be obtained through simple separation after the reaction; the method is few in steps, simple to operate and green, and a new method for synthesizing medical and chemical alcohol compounds is provided for the chemical synthesizing field.

Fluorine-18 Radiolabeling and Radiopharmacological Characterization of a Benzodioxolylpyrimidine-based Radiotracer Targeting the Receptor Tyrosine Kinase EphB4

Members of the Eph receptor tyrosine kinase family play essential roles in the pathogenesis of cancer and are therefore promising candidates for molecular imaging by positron emission tomography (PET), for example. In this regard, radiochemical access to