250665-95-3Relevant articles and documents
Asymmetric synthesis of 1,2-diaryl-2-amino ethanols
Vicario, Jose L.,Badia, Dolores,Carrillo, Luisa,Anakabe, Eneritz
, p. 745 - 751 (2007/10/03)
A straightforward procedure for the asymmetric synthesis of 1,2-diaryl-2-amino ethanols is described. The key step relies on the diastereoselective electrophilic amination of the enolates derived from the corresponding (S,S)-(+)-pseudoephedrine arylacetam
Asymmetric synthesis of arylglycine amino acids using (S,S)-(+)- pseudoephedrine derived amides
Vicario, Jose L.,Badia, Dolores,Dominguez, Esther,Crespo, Ana,Carrillo, Luisa,Anakabe, Eneritz
, p. 7123 - 7126 (2007/10/03)
Arylglycine aminoacids were obtained in good yields and with enantiomeric excesses higher than 99% by using an asymmetric amination reaction protocol on (S,S)-(+)-pseudoephedrine based arylacetamide enolates with di-tert-butylazodicarboxylate. Subsequent hydrazinolysis and hydrolysis yielded the target aminoacids.