250681-69-7

Basic information

• Product Name: 1-BOC-4-(3-CARBOXY-PHENOXY)-PIPERIDINE
• Synonyms: 1-BOC-4-(3-CARBOXY-PHENOXY)-PIPERIDINE;3-(1-Boc-4-piperidyloxy)benzoic acid;4-(3-Carboxy-phenoxy)-piperidine-1-carboxylic acid tert-butyl ester
• CAS NO: 250681-69-7
• Molecular Formula: C₁₇H₂₃NO₅
• Molecular Weight: 321.37
• Mol File: 250681-69-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-BOC-4-(3-CARBOXY-PHENOXY)-PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BOC-4-(3-CARBOXY-PHENOXY)-PIPERIDINE(250681-69-7)
• EPA Substance Registry System: 1-BOC-4-(3-CARBOXY-PHENOXY)-PIPERIDINE(250681-69-7)

Safety Data

• Hazardous Substances Data: 250681-69-7(Hazardous Substances Data)

Usage

Description

1-BOC-4-(3-CARBOXY-PHENOXY)-PIPERIDINE is a chemical compound characterized by the molecular formula C18H25NO5. It features a piperidine ring with a BOC (tert-butyloxycarbonyl) protecting group and a carboxy-phenoxy group. 1-BOC-4-(3-CARBOXY-PHENOXY)-PIPERIDINE serves as a crucial intermediate in the synthesis of pharmaceuticals and organic compounds, known for its versatile reactivity and functional groups, making it a valuable building block in organic synthesis and pharmaceutical research.

Uses

Used in Pharmaceutical Industry:
1-BOC-4-(3-CARBOXY-PHENOXY)-PIPERIDINE is used as a key intermediate in the synthesis of various drugs, including antipsychotics and antiemetics, for its ability to contribute to the development of therapeutic agents with improved efficacy and safety profiles.
Used in Organic Synthesis:
In the field of organic synthesis, 1-BOC-4-(3-CARBOXY-PHENOXY)-PIPERIDINE is utilized as a versatile building block, enabling the creation of a wide range of organic compounds with diverse applications, from pharmaceuticals to specialty chemicals. Its functional groups and reactivity facilitate the synthesis of complex molecules and the exploration of novel chemical reactions.

Upstream product

• 141699-59-4 1-(tert-butoxycarbonyl)piperidin-4-yl methanesulfonate 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 

Downstream Products

• 250682-05-4 N-[2-methyl-5-(3-morpholino-5-trifluoromethylbenzamido)phenyl]-3-(1-tert-butoxycarbonylpiperidin-4-yloxy)benzamide 
• 250681-90-4 N-(5-{3-[N-(2-methoxyethyl)-N-methylamino]benzamido}-2-methylphenyl)-3-(1-tert-butoxycarbonylpiperidin-4-yloxy)benzamide 
• 250681-84-6 N-[2-methyl-5-(3-pyrrolidin-1-ylbenzamido)phenyl]-3-(1-tert-butoxycarbonylpiperidin-4-yloxy)benzamide 
• 250681-81-3 N-[5-(3-fluoro-5-piperidinobenzamido)-2-methylphenyl]-3-(1-tert-butoxycarbonylpiperidin-4-yloxy)benzamide 
• 250681-78-8 N-[2-methyl-5-(3-piperidinobenzamido)phenyl]-3-(1-tert-butoxycarbonylpiperidin-4-yloxy)benzamide 
• 109384-19-2 t-butyl 4-hydroxy piperidine-1-carboxylate 

Relevant articles and documents

NOVEL COMPOUNDS AS DUAL INHIBITORS OF PHOSPHODIESTERASES AND HISTONE DEACETYLASES

It relates to certain compounds having a polycyclic structure and a hydroxamic acid moiety, wherein the polycyclic structure comprises at least three ring systems, wherein one ring system is a polycyclic ring system comprising from 2 to 4 rings; at least one ring is an aromatic ring; and wherein the structure comprises at least 3 nitrogen atoms and 1 oxygen atom. It also relates to a process for their preparation, as well as to pharmaceutical compositions containing them, and to their use in medicine, in particular in the treatment and/or prevention of neurological disorders coursing with a cognition deficit or impairment, or neurodegenerative diseases. wherein B1 is a radical selected from the group consisting of formula (A"), formula (B"), formula (C"), and formula (D"):