250695-50-2Relevant articles and documents
Asymmetric synthesis of 4'-methyl-2',3'-dideoxynucleosides
Luzzio, Frederick A.,Mayorov, Alexander V.,Menes, Michael E.,Champion Jr., William L.
, p. 1977 - 1984 (2007/10/03)
The stereoselective preparation of a 4-methyl-2,3-dideoxyribose derivative is described which utilizes (-)-menthyl pyruvate as a chiral template and an organocerium addition as the key carbon-carbon bond-forming step. The 4-methyl-2,3-dideoxyribose derivative was used as a substrate for a Vorbruggen pyrimidine glycosylation giving an α,β-mixture of 4'-methyl- 2',3'-dideoxynucleosides.