250698-51-2

Basic information

• Product Name: (2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-2-(hydroxymethyl)tetrahydrofuran-3-yl tert-butyl carbonate
• Synonyms: (2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-2-(hydroxymethyl)tetrahydrofuran-3-yl tert-butyl carbonate
• CAS NO: 250698-51-2
• Molecular Weight: 363.318
• Mol File: 250698-51-2.mol
• Article Data: 0

Chemical Properties

• CAS DataBase Reference: (2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-2-(hydroxymethyl)tetrahydrofuran-3-yl tert-butyl carbonate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-2-(hydroxymethyl)tetrahydrofuran-3-yl tert-butyl carbonate(250698-51-2)
• EPA Substance Registry System: (2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-2-(hydroxymethyl)tetrahydrofuran-3-yl tert-butyl carbonate(250698-51-2)

Safety Data

• Hazardous Substances Data: 250698-51-2(Hazardous Substances Data)

Usage

Description

(2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-2-(hydroxymethyl)tetrahydrofuran-3-yl tert-butyl carbonate is a nucleoside and nucleotide analogue belonging to the class of organic compounds. It is a tert-butyl carbonate derivative of a tetrahydrofuran-based nucleoside analogue with antiviral properties. (2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-2-(hydroxymethyl)tetrahydrofuran-3-yl tert-butyl carbonate is designed to mimic the structure of natural nucleosides and is utilized in the development of potential antiviral drugs. The presence of the tert-butyl carbonate group enhances the compound's stability, making it suitable for pharmaceutical applications. Its unique molecular structure makes it a valuable tool for research in the development of new antiviral treatments.

Uses

Used in Pharmaceutical Industry:
(2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-2-(hydroxymethyl)tetrahydrofuran-3-yl tert-butyl carbonate is used as a key intermediate in the synthesis of antiviral drugs. Its antiviral activity and structural mimicry of natural nucleosides make it a promising candidate for the development of new antiviral treatments.
Used in Research and Development:
In the field of medicinal chemistry, this compound is used as a research tool to study the mechanisms of viral replication and to identify potential targets for antiviral drug development. Its unique structure allows researchers to investigate its interactions with viral enzymes and its ability to inhibit viral replication, contributing to the advancement of antiviral therapies.

Downstream Products

• 1562406-27-2 2-(((((2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-3-hydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)benzyl propionate 
• 840506-29-8 (2S)-benzyl 2-(((RS)-(((2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-3-hydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)amino)propanoate 
• 1562406-27-2 2’-deoxy-2’,2’-difluoro-D-cytidine-5’-O-[phenyl(benzyloxy-L-alaninyl)]-(R)-phosphate 
• 1562406-27-2 benzyl ((S)-(((2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-3-hydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate 
• 688008-85-7 5'-O-L-phenylalanylgemcitabine