25078-62-0

Basic information

• Product Name: 2-Propenenitrile, 3-hydroxy-
• CAS NO: 25078-62-0
• Molecular Formula: C3H3NO
• Molecular Weight: 69.0629
• Mol File: 25078-62-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Propenenitrile, 3-hydroxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propenenitrile, 3-hydroxy-(25078-62-0)
• EPA Substance Registry System: 2-Propenenitrile, 3-hydroxy-(25078-62-0)

Safety Data

• Hazardous Substances Data: 25078-62-0(Hazardous Substances Data)

Usage

Physical properties

colorless liquid with a strong, pungent odor, slightly soluble in water

Primary uses

production of pharmaceuticals and agrochemicals, synthesis of industrial chemicals and polymers

Health hazards

toxic if ingested or inhaled, may cause irritation to skin and eyes.

Upstream product

• 131297-23-9 ethyl 3-(N-tert-butylamino)propenoate 

Downstream Products

• 71-30-7 Cytosine 

Relevant articles and documents

Synthesis of α-Cyano Carbonyl Compounds by Flash Vacuum Thermolysis of (Alkylamino)methylene Derivatives of Meldrum's Acid. Evidence for Facile 1,3-Shifts of Alkylamino and Alkylthio Groups in Imidoylketene Intermediates

The syntheses and flash vacuum thermolyses of 5--2,2-dimethyl-1,3-dioxane-4,6-diones (Meldrum's acid derivatives) 13a - i are described.Thermolysis of 13a as well as of ethyl 3-(tert-butylamino)acrylate (22) gives a tautomeric mixture of cyanoacetaldehyde (14) and 3-hydroxypropenenitrile (15).Thermolysis of 13b gives iminoacrolein 26 and not cyanoacetone (29).Thermolysis of 13c, d gives S-methyl cyanothioacetate (30), and 13f - h give cyanoacetamides 31 in high yields. 2-Cyanopent-4-enoic acid derivatives 32 are obtained from Meldrum's acids 13e, i.The results are discussed in terms of facile 1,3-shifts of methylthio and alkylamino groups in imidoylketenes, interconverting imidoylketenes and acylketene imines.