2508-01-2

Basic information

• Product Name: 3-(2-chloroethyl)oxazolidin-2-one
• Synonyms: 3-(2-chloroethyl)oxazolidin-2-one;N-chloroethyl-1,3-oxazolidin-2-one;3-(2-chloroethyl)-1,3-oxazolidin-2-one;3-(2-Chloroethyl)-2-oxazolidinone;3-(2-CHLOROETHYL)OXAZOLIDIN-2-ONE(WXC08388)
• CAS NO: 2508-01-2
• Molecular Formula: C₅H₈ClNO₂
• Molecular Weight: 149.57552
• EINECS: 219-716-1
• Mol File: 2508-01-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 327.2°Cat760mmHg
• Flash Point: 151.7°C
• Appearance: /
• Density: 1.286
• Vapor Pressure: 0.000206mmHg at 25°C
• Refractive Index: 1.484
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 3-(2-chloroethyl)oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-chloroethyl)oxazolidin-2-one(2508-01-2)
• EPA Substance Registry System: 3-(2-chloroethyl)oxazolidin-2-one(2508-01-2)

Safety Data

• Hazardous Substances Data: 2508-01-2(Hazardous Substances Data)

Usage

Description

3-(2-chloroethyl)oxazolidin-2-one is an organic compound that belongs to the oxazolidinone family. It is characterized by its unique chemical structure, which features a five-membered oxazolidinone ring with a chloroethyl group attached to the third position. 3-(2-chloroethyl)oxazolidin-2-one is known for its versatile chemical properties and potential applications in various industries.

Uses

Used in Pharmaceutical Industry:
3-(2-chloroethyl)oxazolidin-2-one is used as an intermediate in the synthesis of various pharmaceutical compounds, particularly those with potential applications in cancer treatment. Its unique structure allows for the development of novel drugs that can target specific biological pathways involved in cancer progression.
Used in Chemical Industry:
In the chemical industry, 3-(2-chloroethyl)oxazolidin-2-one is utilized as a building block for the creation of various chemical products. Its reactivity and functional groups make it a valuable component in the synthesis of complex molecules with specific properties and applications.
Used in Engineering Catalysts:
3-(2-chloroethyl)oxazolidin-2-one is used as an engineering catalyst for selective ester hydrogenation. Its unique chemical properties enable it to facilitate the hydrogenation process, leading to the production of specific ester compounds with high selectivity and efficiency. This application is particularly relevant in the development of green and sustainable chemical processes.

InChI:InChI=1/C5H8ClNO2/c6-1-2-7-3-4-9-5(7)8/h1-4H2

Upstream product

• 124-38-9 carbon dioxide 
• 821-48-7 bis-(2-chloroethyl)amine hydrochloride 
• 107-04-0 1-Bromo-2-chloroethane 
• 20729-41-3 acetaldehyde imine 
• 627-11-2 2-Chloroethyl chloroformate 
• 101973-67-5 (2-chloro-ethyl)-carbamic acid-(2-chloro-ethyl ester) 
• 3356-88-5 N-(2'-hydroxyethyl)-2-oxazolidone 
• 7506-80-1 2-hydroxyethyl (2-hydroxyethyl)carbamate 

Downstream Products

• 4271-26-5 N-vinyl-2-oxazolidone 
• 1421060-11-8 carbonyl chlorohydride{bis[2-(dicyclohexylphosphino)ethyl]amine}ruthenium(II) 
• 86184-78-3 N-(7-chloro-4-quinolyl)-anthranilic acid β-(2-oxo-3-oxazolidinyl)-ethyl ester 
• 86184-79-4 N-(8-trifluoromethyl-4-quinolyl)-anthranilic acid β-(2-oxo-3-oxazolidinyl)-ethyl ester 
• 59849-49-9 (-)-(R)-3-<2-<4-(8-Fluor-10,11-dihydro-2-methyldibenzo thiepin-10-yl)-1-piperazinyl>-aethyl>-2-oxazolidinon 
• 104087-43-6 3-(2-{4-[(1S,3R)-3-(4-Fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-oxazolidin-2-one 
• 104087-44-7 3-(2-{4-[(1R,3S)-6-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-piperazin-1-yl}-ethyl)-oxazolidin-2-one 
• 131727-89-4 N-(phenyl)-N-[1-(2-(2,3,4,5-tetrahydro-2-oxo-oxazol-3-yl)ethyl)-4methoxycarbonyl-4-piperidinyl]-propanamide 
• 13621-80-2 3-(2-phenoxy-ethyl)-oxazolidin-2-one 
• 22455-78-3 3-[2-(N'-phenyl-hydrazino)-ethyl]-oxazolidin-2-one 
• 22455-79-4 3-(2-anilino-ethyl)-oxazolidin-2-one 
• 114458-68-3 3-(2-phenylsulfanyl-ethyl)-oxazolidin-2-one 
• 52548-37-5 3-[2-(4-benzyl-piperazin-1-yl)-ethyl]-oxazolidin-2-one 

Relevant articles and documents

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Chemoselective Hydrogenation of Alkynes to (Z) -Alkenes Using an Air-Stable Base Metal Catalyst

A highly selective hydrogenation of alkynes using an air-stable and readily available manganese catalyst has been achieved. The reaction proceeds under mild reaction conditions and tolerates various functional groups, resulting in (Z)-alkenes and allylic alcohols in high yields. Mechanistic experiments suggest that the reaction proceeds via a bifunctional activation involving metal-ligand cooperativity.

N-(PHOSPHINOALKYL)-N-(THIOALKYL)AMINE DERIVATIVE, METHOD FOR PRODUCING SAME, AND METAL COMPLEX THEREOF

The purpose of the present invention is to provide: a ligand that is useful in a catalytic organic synthetic reaction; a method for producing said ligand; and a metal complex that is useful as a catalyst in an organic synthetic reaction. The present invention provides a compound represented by general formula (1A), a method for producing said compound, and a metal complex including said compound as a ligand. (In the formula, H, N, P, S, L, R1, R2, R3, Q1, and Q2 have the meaning as defined in the Description.)