251350-20-6

Basic information

• Product Name: N-phenethyl-heptanamide
• Synonyms: N-phenethyl-heptanamide
• CAS NO: 251350-20-6
• Molecular Weight: 233.354
• Mol File: 251350-20-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-phenethyl-heptanamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenethyl-heptanamide(251350-20-6)
• EPA Substance Registry System: N-phenethyl-heptanamide(251350-20-6)

Safety Data

• Hazardous Substances Data: 251350-20-6(Hazardous Substances Data)

Upstream product

• 111-70-6 n-heptan1ol 
• 64-04-0 phenethylamine 
• 111-71-7 heptanal 
• 103-63-9 1-phenyl-2-bromoethane 
• 6926-44-9 phenethyl azide 
• 26958-42-9 2-hexyl-[1,3]dithiane 
• 111-14-8 oenanthic acid 
• 2528-61-2 Heptanoic acid chloride 
• 106-30-9 ethyl heptanoate 

Downstream Products

• 2470-68-0 diheptylamine 
• 111-68-2 1-Heptylamine 
• 637359-02-5 heptyl-phenethyl-amine 
• 64-04-0 phenethylamine 

Relevant articles and documents

An efficient, eco-friendly and sustainable tandem oxidative amidation of alcohols with amines catalyzed by heteropolyanion-based ionic liquids via a bifunctional catalysis process

An efficient, eco-friendly and sustainable method for the tandem oxidative amidation of alcohols with amines has been reported. Using heteropolyanion-based ionic liquids as the catalyst and tert-butyl hydroperoxide as the oxidant, this amidation reaction is operationally straightforward and provides a series of primary, secondary and tertiary amides derivatives in moderate to good yields. Solvent-free media, microwave-promoted conditions and reusability of catalysts are the main highlights. Further, the proposed bifunctional catalysis mechanistic pathway has been briefly investigated in this report.

Direct oxidative amidation of aldehydes with amines catalyzed by heteropolyanion-based ionic liquids under solvent-free conditions via a dual-catalysis process

A simple and efficient procedure for the synthesis of amides directly from aldehydes and amines catalyzed by heteropolyanion-based ionic liquids under solvent-free conditions has been reported. The practical protocol was found to tolerate a wide range of substrates with different functional groups. Moderate to excellent yields, solvent-free media, and operational simplicity are the main highlights. The proposed dual-catalysis mechanistic pathway was briefly investigated. Furthermore, the heteropolyanion-based ionic liquids were easily reusable for this oxidative amidation.

Solid-supported chloro[1,3,5]triazine. A versatile new synthetic auxiliary for the synthesis of amide libraries

(equation presented) 2,4,6-Trichloro[1,3,5]triazine was loaded on different types of NH2-functionalized resins to give a new supported reagent. The best results, in term of yields products, were obtained using the chlorotriazine linked to a polystyrene-poly(ethylene glycol) resin. This reagent was employed for the solution-phase synthesis of different amides and dipeptides.