251464-53-6

Basic information

• Product Name: (R)-3-((R)-1-Aminomethyl-butyl)-4-phenyl-oxazolidin-2-one
• Synonyms: (R)-3-((R)-1-Aminomethyl-butyl)-4-phenyl-oxazolidin-2-one
• CAS NO: 251464-53-6
• Molecular Weight: 248.325
• Mol File: 251464-53-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-3-((R)-1-Aminomethyl-butyl)-4-phenyl-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-((R)-1-Aminomethyl-butyl)-4-phenyl-oxazolidin-2-one(251464-53-6)
• EPA Substance Registry System: (R)-3-((R)-1-Aminomethyl-butyl)-4-phenyl-oxazolidin-2-one(251464-53-6)

Safety Data

• Hazardous Substances Data: 251464-53-6(Hazardous Substances Data)

Upstream product

• 2224-37-5 1-nitropentan-2-ol 
• 3156-72-7 (1E)-1-nitropent-1-ene 
• 189350-19-4 (R)-3-((R)-1-Nitromethyl-butyl)-4-phenyl-oxazolidin-2-one 

Relevant articles and documents

Enantioselective synthesis of α-amino acids and monosubstituted 1,2- diamines by conjugate addition of 4-phenyl-2-oxazolidinone to nitroalkenes

The addition of the potassium salt of (R)- or (S)-4-phenyl-2- oxazolidinone to monosubstituted nitroalkenes proceeded with very good diastereoselectivity. Several of the addition products were converted into α-amino acids and monosubstituted 1,2-diamines of high enantiomeric purity.