251565-85-2 Usage
Description
(S)-2-ETHOXY-3-[4-[2-(4-METHANESULFONYLOXY-PHENYL)-ETHOXY]-PHENYL]-PROPIONIC ACID is a complex organic compound with a molecular structure that features a propionic acid backbone, ethoxy and phenyl groups, and a methanesulfonyloxy phenyl moiety. It is characterized by its white solid appearance and possesses unique chemical properties that make it suitable for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
(S)-2-ETHOXY-3-[4-[2-(4-METHANESULFONYLOXY-PHENYL)-ETHOXY]-PHENYL]-PROPIONIC ACID is used as a dual-acting peroxisome proliferator-activated receptor (PPAR) α and γ agonist for its antidiabetic properties. It helps in regulating glucose metabolism and improving insulin sensitivity, making it a promising candidate for the development of novel anti-diabetic drugs.
Used in Chemical Synthesis:
In the chemical synthesis industry, (S)-2-ETHOXY-3-[4-[2-(4-METHANESULFONYLOXY-PHENYL)-ETHOXY]-PHENYL]-PROPIONIC ACID can be utilized as a key intermediate or building block for the synthesis of more complex molecules with potential applications in various fields, such as pharmaceuticals, agrochemicals, and materials science.
Used in Research and Development:
Due to its unique molecular structure and properties, (S)-2-ETHOXY-3-[4-[2-(4-METHANESULFONYLOXY-PHENYL)-ETHOXY]-PHENYL]-PROPIONIC ACID can be employed in research and development for the investigation of new chemical reactions, mechanisms, and the development of novel synthetic methods.
Used in Material Science:
The compound may also find applications in the field of material science, where its unique properties could be exploited to develop new materials with specific characteristics, such as improved stability, enhanced reactivity, or tailored physical properties.
Check Digit Verification of cas no
The CAS Registry Mumber 251565-85-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,5,1,5,6 and 5 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 251565-85:
(8*2)+(7*5)+(6*1)+(5*5)+(4*6)+(3*5)+(2*8)+(1*5)=142
142 % 10 = 2
So 251565-85-2 is a valid CAS Registry Number.
InChI:InChI=1/C20H24O7S/c1-3-25-19(20(21)22)14-16-6-8-17(9-7-16)26-13-12-15-4-10-18(11-5-15)27-28(2,23)24/h4-11,19H,3,12-14H2,1-2H3,(H,21,22)/t19-/m0/s1
251565-85-2Relevant articles and documents
Selective hydrolysis of methanesulfonate esters
Chan, Lai Chun,Cox, Brian G.,Sinclair, Rhona S.
, p. 213 - 217 (2008)
The pH dependence of the hydrolysis of 4-{2-[(methylsulfonyl)oxy]ethyI} phenyl methanesulfonate, 1, and two carboxylate esters, ethyl 2(S)-ethoxy-3-(4-hydroxyphenyl)propionate, 2 and (2S)-2-ethoxy-3-[4-(2-{4- [(methylsulfonyl)oxy]phenyl}ethoxy)phenyl]propanoate, 3, has been studied with a view to the selective removal of any remaining 1, following coupling with 2 to generate 3 in water at 95 °C (Scheme 1). It is shown that reduction of pH from that of the reaction conditions (pH ≈ 10) to pH 7-8 has little effect on the hydrolysis of 1, which is dominated by the water rate over this pH range, but reduces the rate of hydrolysis of the carboxylate ester group by 3 orders of magnitude (pH 7). This very strong quantitative difference in the response of the two types of ester group to pH change allows complete removal of 1 at low pH without measurable loss to the product ester, 3. The conclusions should be generally applicable to the removal of potentially genotoxic alkyl esters of methane sulfonic acid in the presence of carboxylic esters and other base-sensitive groups.
NEW PROCESS
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Page/Page column 6, (2008/06/13)
A process for the preparation of a compound of formula (I); in which R represents H or an acid protecting group which comprises reacting a compound of formula (II); in which R is as previously defined with a compound of formula (III); wherein X is a suitable leaving group in the presence of a base and using water as a diluent.
